TP3

Card Set Information

Author:
islandgirljane
ID:
202681
Filename:
TP3
Updated:
2013-02-23 13:35:02
Tags:
HIV part
Folders:

Description:
HIV Introductory lecture
Show Answers:

Home > Flashcards > Print Preview

The flashcards below were created by user islandgirljane on FreezingBlue Flashcards. What would you like to do?


  1. What is a normal CD4 count?
    500-1500 cells/mm3

  2. What is the life cycle of HIV in the body? 6
    • attachment to host
    • entry
    • reverse transcription
    • viral integration into host DNA
    • viral transcription and translation
    • assembly of the vision and budding
  3. What is step 1 of HIV diagnosis?
    Describe
    • Enzyme Immunoassay (EIA)
    • screening test for abs to HIV
    • result in 60 seconds - 2 days
    • 90-99% sensitivity, 99% specificity
  4. What is step 2 of HIV diagnosis?
    Describe
    • Western Blot
    • confirmatory test to detect specific abs to each viral antigen
    • performed for ALL positive EIA test
    • results in 1-2 weeks
    • 98% sensitivity, 99% specificity
  5. How is AIDS diagnosed?
    • A positive test for HIV abs and one or more of the following:
    • CD4 T cells < 200 (or CD4 < 14%)
    • Any of 25 "AIDs defining conditions"
    • see page 14 of  1st packet
    • Important for exam!!
  6. How many NRTI?
    How many NRTI combos?
    • 7
    • 4
  7. How many NNRTI?
    5
  8. How many Protease Inhibitors?
    9
  9. Name the 2 entry inhibitors?
    • Enfuvirtide (ENF,T20) (Fuzeon)
    • Maraviroc (MVC) (Selzentry)
  10. Name the 2 Integrase inhibitors?
    • Raltegravir (RAL) (Isentress)
    • Elvitegravir (EVG *only available in Stribild*)
  11. How many multiple class combinations?
    Name them an what's in them.
    • 3
    • Atripla (Efavirenz/Emtricitabine/Tenofovir)
    • Complera (Rilipvirine/Emtricitabine/Tenofovir)
    • Stribild (Elvitegravir/Colbicistat/Emtricitabine/Tenovifir)
  12. Abacavir - what is the brand name?
    What class?
    • Ziagen (ABC)
    • NRTI
  13. Didanosine - brand?
    What class?
    • Videx (ddl)
    • NRTI
  14. Emtricitabine - brand?
    What class?
    • Emtriva (3TC)
    • NRTI
  15. Lamivudine - brand?
    What class?
    • Epivir (3TC)
    • NRTI
  16. Stavudine - brand?
    What class?
    • Zerit (d4T)
    • NRTI
  17. Tenofovir - brand?
    What class?
    • Viread (TDF)
    • NRTI
  18. Zidovudine - brand?
    Class?
    • Retrovir (ZDV, AZT)
    • NRTI
  19. What 2 NRTIs are in Epzicom?
    • 3TC/ABC 
    • LAMIVUDINE/ABACAVIR
  20. What 3 NRTIs are in Trizvir?
    • 3TC/ABC/ZDV
    • LAMIVUDINE/ABACAVIR/ZIDOVUDINE
  21. What 2 NRTIs are in Combivir?
    • 3TC/ZDV
    • LAMIVUDINE/ZIDOVUDINE
  22. What are the 2 NRTIs in Truvada?
    • FTC/TDF
    • Emtricitabine/Tenofovir
  23. What are the brand names and class?
    Delaviridine 
    Efavirenz 
    Etravirine 
    Nevirapine 
    Rilipvirine
    • (DLV) (Rescriptor)
    • (EFV) (Sustiva)
    • (ETR) (Intellence)
    • (NVP) (Viramune)
    • (RPV) (Edurant)
    • NNRTIs
  24. Atazanavir - brand & class?
    • (ATV) REYATAZ
    • Protease Inhibitors, hence forth referred to as PIs
  25. Darunavir - brand & class?
    • (DRV) PREZISTA
    • PIs
  26. Fosamprenavir - brand & class?
    • (FPV) LEXIVA
    • PIs
  27. Indinavir - brand & class?
    • (IDV) CRIXIVAN
    • PIs
  28. Lopinavir/ritonavir - brand & class?
    • (LPV/RTV) KALETRA
    • PIs
  29. Nelfinavir - brand & class?
    • (NFV) VIRACEPT
    • PIs
  30. Ritonavir - brand & class?
    • (RTV) NORVIR
    • PIs
  31. Saquinavir - brand & class?
    • (SQV) INVIRASE
    • PIs
  32. Tipranavir - brand & class?
    • (TPV) APTIVUS
    • PIs
  33. What are the 3 types of regimens for starting ART?
    • 2 NRTIs + 1 NNRTI
    • 2 NRTIs + 1 PI (Ritonavir-boosted PI)
    • 2 NRTIs + 1 INSTI
  34. What is the preferred NNRTI based regimen for treatment naive patients?
    • NNRTI based
    • Atripla which is:
    • (Efavirenz/Emtricitabine/Tenofovir)
  35. What is the preferred PI based regimen for treatment naive patients?
    • brand name followed by generic:
    • Reyataz + Norvir +Truvada (Atazanavir/Ritonavir/(Emtricitabine/Tenofovir)
    • or 
    • Prezista + Norvir + Truvada (Darunavir/Ritonavir/(Emtricitabine/Tenofovir)
  36. What is the preferred INSTI based regimen fo treatment naive patients?
    • Isentress + Truvada
    • Raltegravir + (Emtricitabine/Tenofovir)

What would you like to do?

Home > Flashcards > Print Preview