Med Chem III quiz 4

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Author:
ljohnstad
ID:
203156
Filename:
Med Chem III quiz 4
Updated:
2013-02-24 22:50:13
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Med Chem III quiz
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Description:
Med Chem III quiz 4 ANALGESICS
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  1. Extensive first pass when given orally unless resistant to conjegation
    Resistant to conjegation ie codeine
  2. Fentanyl
    Most lipophillic agant transdermal absorption is very good also very dangerous
  3. Labor and dlivery-BBB is poorl developed in infants can lead to
    significant respiratory depression
  4. Metabolism of Anlagesics
    glucronides, N- and Odemethylation occurs in the liver followed by renal excretion
  5. CYP2D6 polymorphisms
    issue and durg clearance rate and side effect profiles
  6. Three sypmptom of a narcotic over dosage
    • ┬áCNS-respiratory Depression
    • CNS- Miosis- pinpoint pupils
    • PNS- Decreased bowl sounds due to relaxed smooth muscle

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