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Metoprolol
Also known as:
Lopressor
-
Metoprolol
Class:
- Selective Beta Blocker
- (class II antiarrythmic)
-
Metoprolol
Mechanism of Action:
Reduction in heart rate, systolic BP, and cardiac output due to selective effects on Beta1 adrenergic receptors. Appears to inhibit tacycardia, especially following an MI.
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Metoprolol
Onset of Action:
Immediate (IV)
-
Metoprolol
Peak Effect:
20 minutes (IV)
-
Metoprolol
Duration:
5 - 8 hours
-
Metoprolol
Half-Life:
3 - 4 hours
-
Metoprolol
Indications:
* Suspected or definate acute MI who are also hypertensive and do not have any contraindications.
* Stable, narrow-complex tachycardia if rhythm remains uncontrolled or unconverted by adeosine or vagel maneuvers o if SVT is recurrent.
* Control ventricular rate in Pt's with A-fib or A-flutter.
* Cretain forms of polymorphic VT (assoc with acute ischemia, familial Long QT Syndrome, catecholaminergic)
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Metoprolol
Contraindications:
- * HR <45 bpm
- * Systolic BP <100 mmHg
- * Heart block
- * Bradycardia
- * Shock
- * Hx of asthma
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Metoprolol
Precautions:
* BP, pulse, ECG must be constantly monitored.
* Atropine and transcutaneous pacing should be available.
-
Metoprolol
Side Effects:
- * bradycardia
- * hypotension
- * lethargy
- * dyspnea
- * wheezing
- * weakness
- * heart block
- * CHF
- * depression
- * bronchospasm
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Metoprolol
Adult Dosage:
Initial bolus of 5mg by slow IV injection. If vitals remain stable, a second 5mg bolus should be given 2 - 5 minutes after the first. If the first two doses are well tolerated,a third bolus of 5mg should be administered 2 - 5 minutes after the second dose.
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Metoprolol
Pedi Dose:
Not indicated
-
Metoprolol
Max Dose:
15mg
-
Metoprolol
Routes of Administration:
Slow IV bolus injection
-
Metoprolol
How Supplied:
Unknown
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