Dementia

Card Set Information

Author:
alvo2234
ID:
204203
Filename:
Dementia
Updated:
2013-02-28 21:24:18
Tags:
Onunka
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Description:
Exam II
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  1. Donepezil
    Aricept
  2. Aricept
    Donepezil
  3. Initial Dose for aricept
    5mg
  4. minimum effective dose for donepezil
    5mg
  5. how long until you adjust dose for aricept
    4-6wks
  6. dosage forms/strengths for aricept
    • OT   (5, 10, 23; do NOT crush or chew)
    • ODT (5, 10)
  7. how do you administer donepezil
    at bedtime with or without food
  8. adrs of donepezil
    • anorexia/weight loss
    • GI effects (NVD)- dose related; slowly titrate
    • HA
    • syncopal episodes
    • insomnia (vivid dreams/nightmares)
  9. rivastigmine
    exelon
  10. exelon
    rivastigmine
  11. oral dosing for exelon
    1.5mg BID (3mg/ day)
  12. how much and how often should the dosage strength of rivastigmine be increased
    3mg/day every 4 wks
  13. exelon transdermal patch dosing
    4.6mg/day
  14. what is the max recommended dosing for the exelon patch
    9.5mg/day
  15. dosage forms for rivastigmine
    • capsule (1.5, 3mg, 4.5, 6mg)
    • patch (4.6, 9.5mg)
    • oral soln (2mg/ml)
  16. how may the exelon soln be taken
    can be taken with water, soda, cold fruit juices
  17. how should rivastigmine be administered
    with meals and the patch should be administered on the upper or lower back
  18. ADRs of rivastigmine
    • anorexia/wt loss
    • GI NVD (may resolve in 1-3 weeks)
    • bradycardia or heart block (with or w/o hx of CVD)
  19. Galantamine
    razadyne
  20. razadyne
    galantamine
  21. razadyne IR initial dosing
    4mg BID
  22. galantamine ER initial dosing
    8mg daily
  23. max dose for razadyne
    24mg daily
  24. max dose of razadyne in a pt with moderate renal or hepatic impairment
    16mg
  25. how much and how ofter must you increase the dose of galantamine
    • IR- 8mg daily every 4 wks
    • ER- 8mg daily every 4 wks
  26. dosage forms for razadyne
    • IR tablets (4, 8, 12mg)
    • ER capsules (8,16, 24mg)
    • oral soln (4mg/ml
  27. how must galantamine be administered
    • take the IR and soln with breakfast and dinner
    • take the ER in the morning with breakfast
  28. memantine
    namenda
  29. namenda
    memantine
  30. memantine IR initial and max dosing
    5-20mg/day
  31. how often and by how much should memantine IR and ERdoses be adjusted by
    • 5mg every >=1wk
    • 7mg every >= 1wk
  32. how often should memantine doses be taken
    one daily; doses > 5mg/day should be divided in 2 doses
  33. initial/max doses for ER memantine
    7-28mg daily
  34. how do you convert memantine IR to ER
    start ER the day after the last IR dose
  35. dosage form for memantine
    • tablet (5, 10mg)
    • oral soln (2mg/ml)
    • combo pack (5, 10mg tablets)
  36. ADRs of memantine
    • HTN
    • HA
    • dizziness
    • diarrhea
    • wt gain or loss
    • vomiting
    • rash
    • hallucinations

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