What are the two main receptors for Ach?
1. How are they named? What specifically?
2. Ionotropic or metabotropic?
3. Predominant in PNS or CNS?
What receptor works with certain poisons? (2)
1. Two functions
2. Found in?
Nicotinic: nicotine, ionotropic, PNS
Muscarinic - muscarine, metabotropic, CNS.
Nicotinic - works with (1) Botox - cosmetic product smoothing skin by causing paralysis; botulism (damaged cans) causing paralysis & death. Antagonist to Ach.
(2) Curare - antagonist to Ach, blocks nicotinic Ach receptor causing quasi paralysis (poison dart frogs).