Leprosy treatments

Card Set Information

Author:
jcu1
ID:
205411
Filename:
Leprosy treatments
Updated:
2013-03-06 15:57:34
Tags:
ID exam
Folders:

Description:
Gillis
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  1. Treatment for Tuberculoid leprosy
    • Dapsone 100 mg po qd PLUS
    • Rifampin 600 mg po qd

    6-12 months
  2. Treatment for Lepromatous leprosy
    • Dapsone 100 mg po qd PLUS
    • Rifampicin 600 mg po qd PLUS
    • Clofazimine 50 mg po qd

    24 months
  3. Dapson MOA
    inhibits dihydropteroate synthase; inhibits folic acid synthesis

    weakly bactericidal
  4. Dapsone dose adjustements
    none
  5. Dapsone AEs
    • screen for G6PD deficiency
    • hepaitis
    • jaundice
    • leukopenia
    • peripheral neuropathy
  6. clofazimine MOA
    DNA binding
  7. clofazimine AES
    skin discoloration - inc melanin pigmentation

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