Pharm - Quiz 8

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Author:
jared.seehawer
ID:
205825
Filename:
Pharm - Quiz 8
Updated:
2013-03-08 02:17:54
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pharmacology chem360
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Description:
Diabetes and Antibiotics through Tetracyclines
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  1. Genetically engineered human insulin:
    Humulin and Novolin
  2. A form of insulin that works even more rapidly than regular insulin:
    Lispro (Humalog)
  3. An intermediate acting form of insulin that in crystalline form:
    • NPH (Neutral Protamine Hagedorn)
    • Humulin N and Novolin N
  4. Long-acting (24 hr) form of insulin:
    Glargine (Lantus)
  5. Family name for oral diabetes drugs which stimulate insulin release from beta cells of the pancreas:
    Sulfonylurea drugs
  6. 3 specific sulfonylreas:
    • glipizide
    • glyburide
    • glimepiride
  7. Common adverse effect of sulfonylreas:
    • increased appetite
    • weight gain
  8. First-line oral diabetic drug which improves receptor sensitivity:
    Metphormin (Glucophage)
  9. 2 drugs that tx diabetes by increasing insulin receptor sensitivity in muscle tissue and adipocytes:
    • rosiglitazone (Avandia)
    • pioglitazone (Actos)
  10. Rosiglitazone causes increased risk of:
    CHF and mortality
  11. Another oral diabetic drug _________ treats diabetes by increasing receptor sensitivity and decreasing ________ in the liver. It's close relative ______ has been taken off the market due to increased risk of _______.
    • pioglitazone
    • gluconeogenesis
    • rosiglitazone (Avandia)
    • CHF
  12. The percent of the blood protein ______ that has reacted with glucose is measured as _________ which is abbreviated as _____. For non-diabetics this % is typically ____ and in ideal diabetics _____ and shouldn't be less than 7%.
    • hemoglobin
    • glycated hemoglobin
    • HbA1c
    • 5-5.5%
    • 6.3%
  13. Oral use of broad spectrum antibiotics can produce superinfection from a resitant bacteria such as _______ _______.
    Clostridium difficile
  14. Penicillin drugs work by inhibiting ________ in Gram (positive/negative) bacteria.
    • transpeptidase (penicillin bind protein)
    • positive
  15. Bacteria can become resistant to penicillins by acquiring the enzyme called _________ or _______ which destroys penicillin.
    • beta lactamase
    • penicillinase
  16. The most common penicillin drug _______ can be combined with _____ _____ which inhibits the enzyme _____.
    • Amoxicillin
    • potassium clavulanate
    • beta lactamase
  17. A common adverse effect of the penicillin family:
    allergic reaction
  18. MRSA stands for ____ _____ _____ _____ and is Gram (positive/negative) and is tx with _____ which is taken (orally/IV).
    • methicillin resistant Staphylococcus aureus
    • positive
    • Vancomycin
  19. Antibiotic family similar to penicillins, _______ that is more active towards Gram ____ bacteria than penicillins.
    • Cephalosporins
    • negative
  20. The cephalosporin used for treating gonorrhea:
    Ceftriaxone (third generation)
  21. Most commonly rx cephalosporin that is used to tx UTIs:
    cephalexin (first generation)
  22. A relative of erythromycin that only requires a 3-5 day regimen, _______, and is concentrated by _ _ _.
    • azithromycin
    • WBCs
  23. Antibiotic family that inhibits bacterial protein synthesis and can be used for pt who are allergic to penicillin:
    Erythromycin family
  24. Antibiotic used to tx gingival pockets and receding gums:
    Periostat
  25. Antibiotic used to tx Lyme's disease, _______, that works on a molecular level by inhibiting ______.
    • Tetracyclines
    • bacterial ribosomes
  26. An infection acquired in the hospital is a _______ infection as opposed to a _______ acquired infection.
    • nosocomial
    • community
  27. _______ is a common alternative drug to penicillin , but should not be taken with mild or used by children.
    tetracycline
  28. A newer member of the tetracycline family that has a longer half-life over the original member of the family:
    Doxycycline

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