BIO immunity

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how are antibodies held together

disulfide bonds
how are antigens made
- four peptide chains
- two heavey
- two light
how many binding sites do antibodies have

2 (Fab)
constant region =

Fc
important to know IgA can be

Dimer and Monomer
IgM has how many binding sites

10
IgD is a
- monomer
- 2 binding sites
IgE is a...

monomer
IgM is a

Pentamer
Which Antibodies go throught the compliment cascade
- IgG
- IgA
which antibody can cross the placenta

IgG
which Antibodies fix compliment
- IgG
- IgM
which antibody is in greatest concentration in serum

IgG 80%
IgG structure =

monomer
Compliment helps antibodies be

more effective
IgG function =
- enhances phagocytosis
- neutralizes toxins and viruses
- protects fetus and newborn
IgM structure =
- pentamer
- binding sites = 10
functions of IgM=
- first antibody produced during primary infection
- effective against microbes and agglutinating antigens
IgA antibody function =
- Localized protection of mucosal surfaces. Provides immunity to infant digestive tract
- only one that goes throgh milk
IgA structure =

Dimer or Monomer
which antibody do they know the least about =

IgD
IgD structure =

monomer
IgG structure =

monomer
functions of IgE
- allergic reactions
- possibly lysis of worms
functions of antibodies =
- tagged bacterial cells
- opsonization =engulfed easier by phagocytes
- neutralization = block binding sites of viruses
- agglutination = block spread
- complement fixation
- Precipitation = antibodies aggregate antigen molecules
4 types of acquiring immunity =
- Natural active = exposed to antigen
- Natural passive = exposed to antibody
- Artificial active = injected with antigen
- Artificial passive = injected with antibody
artificial active immunity =

injected with antigen (flu shot
natural active immunity =

exposed to infections
natural passive immunity
- exposed to antibody
- mother milk IgG
- IgA colostrum
Active passive immunity =
- anti-venom
- Rhogam shots
- no immunological memory
attentuated =

causes immune reponse but not actual infection (organism is live)
two types of active vaccinations =
- killed whole cell
- attenuated
compare inactivated vs attenuated vaccine
- INACTIVATED
- •Dead organisms are safest
- •Generally less effective immunogens
- •Wrong portal of entry
- ATTENUATED
- •Live organisms offer better response
- •Mimic actual infection
- •May mutate back to virulent form

Author:	Anonymous
ID:	205883
Card Set:	BIO immunity
Updated:	2013-03-08 17:33:11
Tags:	BIO immunity
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Description:	BIO immunity
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