BIO immunity

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Anonymous
ID:
205883
Filename:
BIO immunity
Updated:
2013-03-08 12:33:11
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BIO immunity
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BIO immunity
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  1. how are antibodies held together
    disulfide bonds
  2. how are antigens made
    • four peptide chains
    • two heavey
    • two light
  3. how many binding sites do antibodies have
    2 (Fab)
  4. constant region =
    Fc
  5. important to know IgA can be
    Dimer and Monomer
  6. IgM has how many binding sites
    10
  7. IgD is a
    • monomer
    • 2 binding sites
  8. IgE is a...
    monomer
  9. IgM is a
    Pentamer
  10. Which Antibodies go throught the compliment cascade
    • IgG
    • IgA
  11. which antibody can cross the placenta
    IgG
  12. which Antibodies fix compliment
    • IgG
    • IgM
  13. which antibody is in greatest concentration in serum 
    IgG 80%
  14. IgG structure =
    monomer
  15. Compliment helps antibodies be
    more effective
  16. IgG function =
    • enhances phagocytosis
    • neutralizes toxins and viruses
    • protects fetus and newborn
  17. IgM structure =
    • pentamer
    • binding sites = 10
  18. functions of IgM=
    • first antibody produced during primary infection
    • effective against microbes and agglutinating antigens
  19. IgA antibody function =
    • Localized protection of mucosal surfaces. Provides immunity to infant digestive tract
    • only one that goes throgh milk
  20. IgA structure =
    Dimer or Monomer
  21. which antibody do they know the least about =
    IgD
  22. IgD structure =
    monomer
  23. IgG structure =
    monomer
  24. functions of IgE
    • allergic reactions
    • possibly lysis of worms
  25. functions of antibodies =
    • tagged bacterial cells
    • opsonization =engulfed easier by phagocytes
    • neutralization = block binding sites of viruses
    • agglutination = block spread
    • complement fixation
    • Precipitation = antibodies aggregate antigen molecules
  26. 4 types of acquiring immunity =
    • Natural active = exposed to antigen
    • Natural passive = exposed to antibody
    • Artificial active = injected with antigen
    • Artificial passive = injected with antibody
  27. artificial active immunity =
    injected with antigen (flu shot
  28. natural active immunity =
    exposed to infections
  29. natural passive immunity 
    • exposed to antibody
    • mother milk IgG
    • IgA colostrum
  30. Active passive immunity =
    • anti-venom
    • Rhogam shots
    • no immunological memory
  31. attentuated =
    causes immune reponse but not actual infection (organism is live)
  32. two types of active vaccinations =
    • killed whole cell
    • attenuated
  33. compare inactivated vs attenuated vaccine
    • INACTIVATED
    • •Dead organisms are safest
    • •Generally less effective immunogens
    • •Wrong portal of entry
    • ATTENUATED
    • •Live organisms offer better response
    • •Mimic actual infection
    • •May mutate back to virulent form

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