Immune System

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Author:
esellers
ID:
206586
Filename:
Immune System
Updated:
2013-03-11 22:40:48
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Immune System
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Immune Sysytem
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  1. Name 3 surface membrane barriers?
    Skin, mucus, saliva
  2. Name any 2 cellular defenses
    phagocytes, NK cells, lysosomes
  3. Phagocytes in the liver are called
    Keffer cells
  4. Phagocytes in the skin are called
    langerhans
  5. Phagocytes in connective tissue are called
    histocytes
  6. Phagocytes engulf antigen and become_______ and combine with lysosomes to form________.
    phagosomes, phagolysosme
  7. Phagocytes can be formed from
    neutrophils
  8. Neutrophils produce a chemical by the name
    defensins
  9. Generation of free radicals is by
    respiratory burst
  10. Difference between neutrofhils and phagocytes
    Neutrophils destory and phagocytes survive
  11. Coating of antigens with chemicals by phagocytes is called
    opsonization
  12. Null cells are also called ______ and______
    NK cells or 3rd population cells
  13. 5 cardinal signs of inflammation
    heat, pain, swelling, redness, impair
  14. Primary role of inflammatory chemicals is to
    dilate small vessels
  15. Name 4 inflammatory chemicals
    histamine, kinin, PG's, complement, lymphokine
  16. Lining of phagocytes near the wall of the blood vessel is called
    margination
  17. Movement of phagocytes from the vessel to the inflammatory area is
    diapedesis
  18. Pus is
    neutrophiles, tiessue, pathogens
  19. If inflammation fails______ is formed.
    Abcess
  20. Name 2 antimicrobial proteins
    complement, interferon
  21. Factors B,D,and P are
    complements
  22. Interferon role in immunity is to
    stop viral replication
  23. Lymphocytes produce____interferon where as leukocytes produce_______
    gamma, alpha
  24. Fever is caused by the chemical_______secreted by______
    Pyrogen, macrophages
  25. B and T lymphocytes mature in ______ and _______ respectively.
    thymus, bursa
  26. Self tolerance is due to the presence of _______, a base for lymphocyte education.
    self antigens
  27. Incomplete antigens are called_______
    Haptens
  28. Incomplete antigens can combine with body proteins to produce_____
    valence
  29. Active antigenic determinants on anitgen is indicated by the word_________
    Valence
  30. PVC is used in hip replacement because of its
    O'valence
  31. Pulling all antigenic sites on to the receptors of B cells is called________
    capping
  32. Memory cells are the descendants of_____born the process of_______
    B-Lymphocytes, clonal selection
  33. Weak antigens are also called as________ antigens
    attenuated
  34. Antibodies are also called as________and these are______-proteins
    immunoglobins, soluble
  35. An anitbody has ____chains
    four
  36. IgD and IgM are found on
    b-cell receptors
  37. The type of anitbody that is first released due to immune response is
    IgM
  38. Most abudent anitbody in the body is
    IgG
  39. IgA is primarily in_____secretions
    mucus
  40. Trounble maker anitbody is
    IgE
  41. The antobodies which fixes the complement are _____ and ______
    Igm and IgG
  42. Antobody diversity is not due to genes but due to _____ recombination
    Somatic
  43. Agglutination is due to
    IgM
  44. Precipitation process is due to
    insoluble proteins
  45. B lymphocytes are fused to tumor cells to form
    hybridoma
  46. High purity and high specificity is shown by ______ antibodies
    monoclonal
  47. Name the 3 types of T cells involved in immune response
    cytotoxic, helper, suppressor
  48. CD4 cells are
    primary cells
  49. CD8 cells are _____ & ______
    cytotoxic and suppressor
  50. Activated T cells release soluble glycoproteins called _____ or ______
    cytokines or lymphokines
  51. Macrophages release ______ which stimulate T cells
    monokines
  52. T cell proliferation is aided by
    I12
  53. ______ are called the Directors of the immune system
    helper t-cells
  54. Cytotoxic T cells directly attack antigens by a process called
    lethal hit
  55. The toxin that is released by cytotoxic T cells into the target cell is
    perforin
  56. Non sensitized T cells become activated to cytotxic T cells is
    Interferon
  57. Uncontrolled autoimmune response is prevented by the action of
    suppressor T-cell
  58. Transplant of tissue on the same person from different sites is called
    autografts
  59. Transplant of tissue from one person to the other is
    allograft
  60. Transplant of organs between twins is
    isograft
  61. Interspecies transplants of tissue or organs comes under the category of _____ grafts
    xeno
  62. Intraspecies transplants are called
    allografts
  63. One of the widely and commonly used immunosuppressive drug is
    Cyclosporine
  64. Thymic aplasia is due to
    undeveloped thymus
  65. Hodgkins disease is due to
    lymph cancer
  66. Deficit of both B and T cells causes
    SCID
  67. Fetal tissue transplant to the adult of same species is an example for
    allografts
  68. An antigen eliciting a normal immune response is called
    allergen
  69. Anaphylaxis is caused by
    IgE and allergen crosslink
  70. Anaphylactic shock symptoms can be reversed by
    epinephrines
  71. Anaphylaxis an be cured by this class of drugs
    antihistamines
  72. Farmers lung and mushroom growers lung are examples of
    Type III
  73. Mismatched transfussions is an example of
    Type II
  74. Spontaneous allergy to enviromental antigens is called
    atopy
  75. Allergic contact dermatitis is an example of
    Type II
  76. Autoimmune thrombocytes is a disorder caused by
    destruction of platelets
  77. Opiate neuropeptides can act both as _____ and _____
    neural and immuno stimulant
  78. Pruple lesions of the skin in Aids patients is called
    Kaposis sarcoma
  79. Normal CD4 cell count is in the range of
    600-1200

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