Path & Pharm II

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Path & Pharm II
2013-03-12 10:58:12
Lesson 12 Antihistamines

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  1. what is allergic conjunctivitis?
    when the body's immune system becomes sensitized and overreacts to something that is ordinarilly harmless
  2. when does an allergic reaction occur?
    when "something" an allergan comes into contact with your eye
  3. what cells do the allergan release and what do they release?
    mast cells and histamine
  4. What are eye allergy symptoms?
    watery eye, itchiness, sensitivity to light, redness, eyelid swelling
  5. How do you treat allergies?
    ocular decongestants, antihistmamines and mast cell stabilizers
  6. What are ocular decongestants?
    contrist the superficial blood vessels and decrease associtated redness
  7. What are antihistamines?
    block histamine and reduce the resulting symptoms
  8. What are mast cell stabilizers?
    prevent the initial process of degranulation from occuring
  9. What is Alocril & what does it do?
    nedocromil sodium 2% & it acts as a mast cell stabilizer
  10. What are some reactions to Alocril?
    headache, ocular burning, irritation and stinging, unpleasant taste, nasal congestion
  11. What is Optivar & what does it do?
    azelastine hydrochloride 0.05% & it is selective H1 antagonist and an inhibitor of release of histamine
  12. What are some reactions to Optivar?
    eye burning/stinging, headaches, bitter taste, dyspnea, eye pain, fatigue, influenza like symptoms, pharyngitis, rhinitis, and temporary blurring
  13. What is Alaway (Bausch & Lomb)?
    ketotifen solution 0.025% & second- generation non competitive H1-antihistamine and mast cell stabilizer
  14. What are reactions with Alaway?
    headache, dry eyes, eyelid disorder, itching, keratits, lacrimation disorder, mydriasis, photophobia
  15. What is Pantanol & what is so important about it?
    olopatadine hydrochloride 0.1% & it is was off patent and available OTC
  16. What is Pataday & what does it do?
    olopatadine hydrochloride solution 0.2% & Alcon's prescription allergy drop and it is known as patanol or opatanol solution
  17. What is Alamast & what does it do?
    pemirolast potassium ophthalmic solution 0.1% & it is a mast cell stabilizer that inhibits the in-vito type I immediate hypersensitivity
  18. What are some reactions to Alamast?
    burning, dry eye, foreign body sensation, ocular discomfort