Path & Pharm II
Card Set Information
Path & Pharm II
Lesson 12 Antihistamines
what is allergic conjunctivitis?
when the body's immune system becomes sensitized and overreacts to something that is ordinarilly harmless
when does an allergic reaction occur?
when "something" an allergan comes into contact with your eye
what cells do the allergan release and what do they release?
mast cells and histamine
What are eye allergy symptoms?
watery eye, itchiness, sensitivity to light, redness, eyelid swelling
How do you treat allergies?
ocular decongestants, antihistmamines and mast cell stabilizers
What are ocular decongestants?
contrist the superficial blood vessels and decrease associtated redness
What are antihistamines?
block histamine and reduce the resulting symptoms
What are mast cell stabilizers?
prevent the initial process of degranulation from occuring
What is Alocril & what does it do?
nedocromil sodium 2% & it acts as a mast cell stabilizer
What are some reactions to Alocril?
headache, ocular burning, irritation and stinging, unpleasant taste, nasal congestion
What is Optivar & what does it do?
azelastine hydrochloride 0.05% & it is selective H1 antagonist and an inhibitor of release of histamine
What are some reactions to Optivar?
eye burning/stinging, headaches, bitter taste, dyspnea, eye pain, fatigue, influenza like symptoms, pharyngitis, rhinitis, and temporary blurring
What is Alaway (Bausch & Lomb)?
ketotifen solution 0.025% & second- generation non competitive H1-antihistamine and mast cell stabilizer
What are reactions with Alaway?
headache, dry eyes, eyelid disorder, itching, keratits, lacrimation disorder, mydriasis, photophobia
What is Pantanol & what is so important about it?
olopatadine hydrochloride 0.1% & it is was off patent and available OTC
What is Pataday & what does it do?
olopatadine hydrochloride solution 0.2% & Alcon's prescription allergy drop and it is known as patanol or opatanol solution
What is Alamast & what does it do?
pemirolast potassium ophthalmic solution 0.1% & it is a mast cell stabilizer that inhibits the in-vito type I immediate hypersensitivity
What are some reactions to Alamast?
burning, dry eye, foreign body sensation, ocular discomfort