Adenosine

&lt;50 kg: 0.05 - 0.1 mg/kg (max of 0.3 mg/kg/dose) up to 12 mg.
&gt;50 kg: same as adult dose.

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Adenosine

Names / Class

Adenocard

Class V Antiarrythmic
Adenosine

Mechanism of Action

Reduces conduction of electrical impulse through the AV node and interrupts reentry pathway in PSVT.
Adenosine

Onset of Action
Peak Effect
Duration
Half-Life
- 20 - 30 seconds
- 20 - 30 seconds
- 30 seconds
- 10 seconds
Adenosine

Indications

Tachyarrythmias refractory to vagal maneuvers.
Adenosine

Contraindications
- Irregular A-Fib
- Polymorphic tachycardia
- 2nd or 3rd degree heart block
- Sick sinus syndrome
- Known hypersensitivity to med
Adenosine

Precautions
- Use caution in Pts with asthma
- Arrythmias at time of cardioversion (generally lasting only a few seconds)
- Transient asystole in extreme cases
Adenosine

Side Effects
- Facial flushing
- HA
- SOB
- Dizzyness
- Nausea
Adenosine

Adult Dose
- 6 mg rapid IV or IO bolus over 1 - 2 seconds followed immediately by a rapid saline flush.
- 2nd dose after 1 - 2 minutes if needed:
- 12 mg rapid IV or IO bolus over 1 - 2 seconds followed immediately by a rapid saline flush.
- ***should be delivered to closest available vein to the heart***
Adenosine

Pedi Dose
- <50 kg: 0.05 - 0.1 mg/kg (max of 0.3 mg/kg/dose) up to 12 mg.
- >50 kg: same as adult dose.
Adenosine

Max Dose

12 mg

Per 2010 AHA guidelines: no more than 2 doses should be given (6 mg first dose, followed by 1 dose of 12 mg).
Adenosine

Routes / How Supplied

IV or IO bolus directly into closest possible vein to heart

Vial