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Names / Class
Mechanism of Action
- Increased cardiac contractility & HR (beta1)
- Vasoconstriction (alpha)
- = increased systolic BP & pulse pressure
Onset of Action
- <5 minutes
- 5 - 8 minutes
- <10 minutes
- 2 minutes
- Hemodynamically significant hypotension: systolic 70 - 100 mmHg NOT resulting from hypovolemia, & cardiogenic shock.
- Symptomatic bradycardia refractory to Atropine.
- Hypovolemic shock in which fluid resuscitation has not occurred.
- Pheochromocytoma (tumor in the adrenal gland).
- Severe tachyarrythmias
- Ventricular irritability
- Reduce dose if Pt taking MAOIs (type of antidepressant)
- Beneficial effects lost when dose exceeds 20 mcg/kg/min
- Can be deactivated with alkaline solutions such as sodium bicarbonate.
- Nausea / Vomiting
- ** Many side effects are dose related **
- 800mg in 500mL D5W
- 400mg in 250mL D5W (1600 mcg/mL)
- 2 - 10 mcg/kg/min increased until BP improves or until max dose of 20 mcg/kg/min
- IV drip should be piggybacked into an already established IV infusion
2 - 20 mcg/kg/min
Route / How Supplied
IV drip only - piggybacked into existing IV infusion
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