Dobutamine

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Author:
Ritameeker
ID:
206903
Filename:
Dobutamine
Updated:
2013-03-12 20:58:35
Tags:
Dobutamine Dobutrex Sympathetic Agonist paramedic study
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Description:
Dobutamine / Dobutrex
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  1. Dobutamine

    Names / Class
    Dobutrex

    Sympathetic Agonist
  2. Dobutamine

    Mechanism of Action
    Inotropic effect increases cardiac contractility.  Little chronotropic effect, so HR is not increased.
  3. Dobutamine

    Onset of Action
    Peak Effect
    Duration
    Half-Life
    • 2 - 10 minutes
    • 10 - 20 minutes
    • Varies
    • 2 minutes
  4. Dobutamine

    Indications
    Short term management of CHF when increased cardiat output WITHOUT increased HR is desired.
  5. Dobutamine

    Contraindications
    • Inadequate HR
    • Should not be used as the sole agent in hypovolemic shock unless fluid resuscitation is well under way.
  6. Dobutamine

    Precautions
    • Ventricular irritability
    • May be ineffective if Pt is on beta blockers
    • Use with caution following MI
    • Can be deactivated by alkaline solutions such as sodium bicarbonate
    • Tachycardia & increases systolic BP are common following administration
    • Increased HR of >10% may induce myocardial ischemia
    • PVC can occur
  7. Dobutamine

    Side Effects
    • HA
    • HTN
    • Nervousness
    • Arrythmias
    • Palpitations
    • CP
    • Dyspnea
    • Nausea / Vomiting
    • *** Many side effects are dose related
  8. Dobutamine

    Adult Dose
    • Dilute:
    • 250mg in 500mL of D5W (0.5 mg/mL)
    • OR
    • 250mg in 1L of D5W (0.25 mg/mL)

    • 2 - 20 mcg/kg/minute is the desired dose range
    • 5 - 10 mcg/kg/min is the common range
    • Administer according to Pt response
  9. Dobutamine

    Pedi Dose
    2 - 20 mc/kg/min
  10. Dobutamine

    Max Dose
    20 mcg/kg/min
  11. Dobutamine

    Routes / How Supplied
    IV drip only - best administered via controlled pump

    Vial

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