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Names / Class
Mechanism of Action
Inotropic effect increases cardiac contractility. Little chronotropic effect, so HR is not increased.
Onset of Action
- 2 - 10 minutes
- 10 - 20 minutes
- 2 minutes
Short term management of CHF when increased cardiat output WITHOUT increased HR is desired.
- Inadequate HR
- Should not be used as the sole agent in hypovolemic shock unless fluid resuscitation is well under way.
- Ventricular irritability
- May be ineffective if Pt is on beta blockers
- Use with caution following MI
- Can be deactivated by alkaline solutions such as sodium bicarbonate
- Tachycardia & increases systolic BP are common following administration
- Increased HR of >10% may induce myocardial ischemia
- PVC can occur
- Nausea / Vomiting
- *** Many side effects are dose related
- 250mg in 500mL of D5W (0.5 mg/mL)
- 250mg in 1L of D5W (0.25 mg/mL)
- 2 - 20 mcg/kg/minute is the desired dose range
- 5 - 10 mcg/kg/min is the common range
- Administer according to Pt response
2 - 20 mc/kg/min
Routes / How Supplied
IV drip only - best administered via controlled pump
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