Procainamide

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Author:
Ritameeker
ID:
206915
Filename:
Procainamide
Updated:
2013-03-12 21:37:07
Tags:
Procainamide Pronestyl Sodium channel blocker antiarrythmic paramedic study
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Description:
Procainamide / Pronestyl
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  1. Procainamide

    Names / Class
    Pronestyl

    1A Sodium channel blocker, antiarrythmic
  2. Procainamide

    Mechanism of Action
    • Slows conduction through myocardium.
    • Elevates ventricular fibrillation threshhold.
    • Suppresses ventricular ectopic activity.
  3. Procainamide

    Onset of Action
    Peak Effect
    Duration
    Half-Life
    • 10 - 30 minutes
    • 15 - 20 minutes
    • 3 - 6 hours
    • 3 hours
  4. Procainamide

    Indications
    • V-Tach with a pulse
    • Pre-excited A-Fib
  5. Procainamide

    Contraindications
    • 2nd & 3rd degree heart block
    • Severe conduction system disturbances
    • CHF
    • Should be avoided in Pts with prolonged QT syndrome
  6. Procainamide

    Precautions
    • Monitor CNS toxicity
    • Hypotension (with IV infusion)
    • Monitor BP
    • Hypotensive effects may increase if given with antiypertensive meds
    • Chance of neurotoxicity if given with Lidocaine
  7. Procainamide

    Side Effects
    • Drowsiness
    • Seizures
    • Confusion
    • Hypotension
    • Anxiety
    • Nausea
    • Vomiting
    • Convulsions
    • Widening of QRS complex
    • Bradycardia
    • Heart block
    • Respiratory & cardiac arrest
  8. Procainamide

    Adult Dose
    20 - 50 mg/min until arrythmia suppressed.

    • * D/C if:
    • Arrythmia suppressed
    • Hypotension
    • QRS complex widened by 50%
    • Total of 17 mg/kg given

    • Slow IV bolus: 20 mg/kg followed by maintenance infusion.
    • Maintenance Infusion: 1 - 4 mg/min
  9. Procainamide

    Pedi Dose
    Not indicated
  10. Procainamide

    Max Dose
    17 mg/kg
  11. Procainamide

    Route / How supplied
    • Slow IV bolus
    • IV drip

    Vial

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