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Water attaches, to it
ex. Phosphate head of phospholipid bilayer
repelled by water
ex. Lipid tails of phospholipid bilayer
Intracellular (inside the neuron)
K+ , protein- (amino acids)
--not equal concentration
branched like extentions
Extracellular (outside Neuron)
Na+ (very positive) + mvolt
Bring Positive ions in neuron.
A change in the RMP
Occurs on the dendrites or cell body
+ ions are depolarizing(+ions come across
a separation of change across a membrane
RMP becomes more (-)
+ ions come across membrane
Becomes more positive
Amount of depolarization required to generate an impulse (Current flowing down an axon).
how do ions move across the membrane?
by channel proteins
what are the 4 channel proteins?
1. Leak Channel
2. Chemically Gated Channel
3. Voltage Gated Channel
4. Mechanically Gated Channel
K+ is always leaking........
Na+ is always leaking........
Leak ions back and forth A.M.
...out of cell
.....in the cell at slower rate
Chemically gated channel
A chemical bonds to membrane to open an ion channel.
Na+/K+ Exchange pump
3 Na+ out &
2 K+ in
Voltage Gated Channel
Respond to a change in the trasmembrane ptential ( RMP)
When RMP -70mV reach treshold (-55mV) Na+ gates open axon action potential
Neurons ions physiology
Physiology of neurons