BIO disorders in immmunity

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BIO disorders in immmunity
2013-03-14 09:11:28
BIO disorders immunity

BIO disorders in immunity
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  1. autoimmune disoders are caused by
    lack or loss of slef antigen recognition
  2. Type I hypersensitivity =
    • immediate (IgE and histamine)
    • ie. hay fever
    • over production of histamine
  3. Type II hypersensitivity
    • Cytotoxic (IgG and complement)
    • blood type mismatch
  4. Type III hypersensitiviy =
    Immune Complex (IgG complexes)
  5. Type IV hypersensitivity =
    delayed (T cells and cytokines)
  6. what do corticosteriods do
    inhibit T-cells
  7. Cromolyn does what
    blocks degranulation
  8. antihistamines block
  9. what is the casue of a typical asthma response
  10. how do allergy shots work
    • the shot provokes IgG response
    • IgG binds antigen
    • IgE response is reduced
  11. If a person is given the wrong type of blood what happens
    • the antibody interacts with the antigen (wrong blood type) and causes complement activation
    • the foreign blood cells are lysed
  12. what antibody is usually associated with blood type mismatch reaction 
  13. Anti A and B antibodies are made
    due to exposure to similar A and B anitgens found in food particles and called naturally ocurring antibodies
  14. AB blood makes which antibodies
  15. Type O blood makes which type of antibodies
    both A and B
  16. if mother is Rh D - what happens
    if baby is Rh D + the mother makes anti-Rh D and IgG from the mom crosses the placental boarder and lyses the babies cells
  17. what are examples of Type III hypersensitivity
    rheumatoid arthritis and lupus
  18. what is type III hypersensitivity
    • antibody complexes form with anitgens to make a maromolecule that deposits in tissues
    • comlemne t is activited an nearby tissue damage results
  19. what is special about the time frame of Type IV hypersensitivity
    • there is a delayed response up to two days
    • involves a special kind of T-cell
    • example = tuberculin skin test
  20. urushinol =
    • chemical agent in plant sap that combines with skin protein
    • triggers T-cell response
    • subsequent exposure results in inflammation
    • ie poison IVY
  21. what type of hypersensitivity is organ donor tissue rejection
    Type IV
  22. what is SCID
    • boy in the bubble disease
    • no B or T cells
  23. agammaglobulinemia =
    no B cell defense
  24. Hypogammaglobulinemia =
    little B cells defense
  25. DiGeorge Syndrome =
    no T cell defense