DNA synthesis-proteins involved

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Author:
efrain12
ID:
207560
Filename:
DNA synthesis-proteins involved
Updated:
2013-03-15 22:24:10
Tags:
bios
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Description:
proteins involved in dna synthesis
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  1. Helicase (opening the helix)
     
    -catalyzes the breaking of hydrogen bonds between base pairs and the opening of the double helix
  2. (opening the helix) Single strand DNA-binding proteins
    stabilize single-stranded DNA
  3. (opening the helix) Topoisomerase
    -breaks and rejoins the DNA double helix to relieve twisting forces caused by the opening of the helix
  4. (leading strand) Primase
    catalyzes the synthesis of the RNA primer
  5. (leading strand) DNA polymerase III
    extends the leading strand
  6. (leading strand) Sliding clamp

    holds DNA polymerase in place during strand extension
  7. (lagging strand) Primase
    catalyzes the synthesis of the RNA primer on an Okazaki fragment
  8. (lagging strand) DNA polymerase III
    extends an okazaki fragment
  9. (lagging strand) Sliding clamp
    holds DNA polymerase in place during strand extension
  10. (lagging strand) DNA polymerase I
    removes the RNA primer and replaces it with DNA
  11. (lagging strand) DNA ligase
    catalyzes the joining of okazaki fragments into a continuous strand

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