Plavix

Card Set Information

Author:
Ritameeker
ID:
207639
Filename:
Plavix
Updated:
2013-03-16 11:53:39
Tags:
Plavix Clopidogrel platelet aggregation inhibitor ADP paramedic drug study
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Description:
Plavix / Clopidogrel
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  1. Plavix

    Names / Class
    Clopidogrel

    Platelet Aggregation Inhibitor
  2. Plavix

    Mechanism of Action
    Inhibits platelet aggregation by selectively binding to the ADP receptors on the surface of platelets & binding fibrogen to the GP IIb-IIIa receptor on activated platelets.
  3. Plavix

    Onset of Action
    Peak Effects
    Duration
    Half-Life
    • 2 hours
    • 3 - 7 days
    • 7 - 10 days
    • 7 - 8 days
  4. Plavix

    Indications
    • Acute coronary syndrom
    • Recent MI
    • Stroke
    • Peripheral Vascular Disease (PVD)
  5. Plavix

    Contraindications
    • Hypersensitivity to the drug
    • Hemostatic disorder
    • Active pathological bleeding (peptic ulcer, or intracranial bleeding)
  6. Plavix

    Precautions
    Pts taking NSAIDs (nonsteroidal anti-inflammatory)
  7. Plavix

    Side Effects
    • Increased risk of bleeding
    • Fever
    • Allergic reactions
    • Myalgias
    • Arthralgias
    • Bronchospasm
    • Skin rash
  8. Plavix

    Adult Dose
    • Acute Coronary Syndrome & Non ST elevation ACS:
    • 300 mg loading dose, followed by 75 mg once daily in combination with Aspirin.
    • STEMI:
    • 75 mg once daily in combination with Aspirin (with or without a loading dose, and with or without thrombolytics)
    • Recent MI, Stroke, or PAD:
    • 75 mg once daily.
  9. Plavix

    Pedi Dose
    Not Indicated
  10. Plavix

    Max Dose
    • 75 mg daily
    • (300 mg - loading dose)
  11. Plavix

    Routes / How Supplied
    PO

    Unknown

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