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Flumazenil(Romazicon)
Dose/Route?
Dosage: 1G/kg mixed with at least 6-8oz of water then PO or via an NG tube
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Flumazenil(Romazicon)
Precautions?
Administer only after emesis or in the cases where emesis is contraindicated
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Flumazenil(Romazicon)
Indications?
Acute ingested poisonings
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Flumazenil(Romazicon)
Description?
Is specially prepared charcoal that will absorb and bind toxin from the gastrointestinal tract.
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Flumazenil(Romazicon)
Class?
Absorbent
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Flumazenil(Romazicon)
dosage/route?
0.2mg IV over 30secs/min up to 1mg
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Flumazenil(Romazicon)
Precautions?
Hepatic impairment, elderly, pregnant, nursing mothers, head injury, alcohol and drug dependency and physical dependence on benzodiazepines
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Flumazenil(Romazicon)
Contraindications?
Hypersensitivity to flumzenil or benzodiazepines; those patients who take medications for status epilepticus or seizures, seizure-prone pts during labor and delivery; tricycle antidepressant overdose.
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Flumazenil(Romazicon)
Indications?
Respiratory depression secondary to the benzodiazepines
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Flumazenil(Romazicon)
Description?
Flumazenil is a benzodiazepine antagonist used to reverse the sedative and recall the psychomotor effects of diazepam, midazolam, and the other benzodiazepines.
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Flumazenil(Romazicon)
Class?
Benzodiazepine Antagonist
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Naloxone(Narcan)
Dose/Route?
- Adult: 0.4-2mg IV/IM/IN repeated 2-3 minutes as needed up to 10mg
- Pedi: 0.01mg IV//IM repeated every 2-3 minutes as needed up to 10 mg
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Naloxone(Narcan)
Precautions?
Possible dependency(including newborns). it also has a half life that is shorter then most narcotics; hence the pt may return to the overdose state.
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Naloxone(Narcan)
Contraindications?
Hypersensitivity to the drug, non-narcotic induced respiratory depression.
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Naloxone(Narcan)
Indication?
Narcotic and synthetic narcotic overdose; coma of unknown origin
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Naloxone(Narcan)
Description?
Naloxone is a pure narcotic antagonist that blocks the effects of both natural and synthetic narcotics and may reverse respiratory depression.
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Naloxone(narcan)
Class?
Narcotic Antagonist
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Lorazepam(Ativan)
Dosage/Route?
- Dosage/Route: Sedation: 2 to 4 mg IM,
- 0.5 to 2 mg IV
- Pedi:
- 0.03 to 0.5 mg/kg IV/IM/PR up to 4 mg.
Status Epilepticus: 2 mg slow IV/PR ( 2 mg/min.)
- Pedi:
- 0.1 mg/kg slow IV/PR ( 2 to 5 min.)
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Lorazepam(Ativan)
Precautions
- Precautions: Narrow –angle glaucoma, depression or psychosis, coma,
- shock, acute alcohol intoxication, renal or hepatic impairment, organic brain
- syndrome, myasthenia gravis, GI disorders, elderly, debilitated, limited
- pulmonary reserve.
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Lorazepam(Ativan)
Contraindications?
Contraindications: Sensitivity to benzodiazepines.
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Lorazepam(Ativan)
Indications?
- Indications : Sedation
- for cardioversion and status epilepticus.
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Lorazepam(Ativan)
Description?
- Description: Lorazepam ( Ativan ) is the most potent benzodiazepine
- available. It has strong antianxiety, sedative, hypnotic, and skeletal relaxant
- properties. Also a relatively short half-life.
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Lorazepam(Ativan)
Class?
Sedative
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Midazolam(Versed)
Dosage/Route: 1 to 5 mg slow IV
Pedi: 0.05 to 0.2 mg/kg IV; 0.1 to 0.15 mg/kg IM
Intranasal: 3 mg
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Midazomlam(Versed)
Precautions?
Precautions: COPD, renal impairment, CHF, elderly.
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Midazolam(Versed)
Contraindications?
- Contraindications: Hypersensitivity to benzodiazepines, narrow-angle glaucoma,
- shock, coma, or acute alcohol intoxication.
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Midazolam(Versed)
Indications?
- Indications: To
- induce sedation before cardioversion or intubation, and seizures.
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Midazolam(Versed)
Description?
- Description: Midazolam ( Versed ) is a short-acting benzodiazepine with
- CNS depressant, muscle relaxant, anticonvulsant, and anterograde amnestic
- effects.
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Midazolam(Versed)
Class?
Sedative
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Diazepam(valium)
Dose/route?
- Dosage/Route: Seizures: 5 to 10 mg
- IV/IM.
- Acute anxiety: 2 to 5 mg IV/IM Pedi: 0.5-2 mg IM
- Premedication: 5 to15 mg IV, Pedi: 0.2 to 0.5 mg/kg IV
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Diazepam(valium)
contraindication?
- Contraindications: Hypersensitivity
- to the drug, shock, coma, acute alcoholism, depressed
- vital signs, obstetric patients, and neonates.
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Diazepam(valium)
precautions?
- Precautions: Psychoses, depression, myasthenia gravis. Due to a
- short-half life of the drug, seizure activity may recur.
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Diazepam(valium)
Indications?
- Indications:
- Major motor seizures, status epilepticus, premedication before cardioversion,
- muscle tremors due to injury, and acute anxiety.
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Diazepam(valium)
Description?
- Description: Diazepam ( Valium ) is a benzodiazepine sedative and
- skeletal muscle relaxant that reduces tremors, induces amnesia, and reduces the
- incidence and recurrence of seizures. It relaxes muscle spasms in orthopedic
- injuries and produces amnesia for painful procedures ( cardioversion).
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Diazepam(valium)
Class?
Anti-anxiety, Hypnotic, Anti-convulsant, Sedative
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