OSD6 quick study

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OSD6 quick study
2013-03-17 03:59:47
OSD6 quick study

OSD6 quick study
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  1. Smoking decreases risk
    Recurrent apthous stomatitis
  2. Pathergy test
    Behcet Syndrome
  3. Crops of mouth ulcers, genital ulcers, eye inflammation
    Behcet Syndrome
  4. STDs/Chlamydia
    Reactive Arthritis (Reiter's Syndrome)
  5. Hemorrhagic crusting of vermillion borders of the lips
    Erythema multiforme
  6. Bulls eye skin lesions
    EM Minor
  7. Steven's Johnson syndrome
    EM Major
  8. Dekeratinization and desquamation of filiform papillae
    Geographic Tongue
  9. Ageusia, Dysgeusia, lichenoid reaction, epithelial sloughing
    Allergic Contact Stomatitis
  10. Labial enlargement and facial swelling
    Melkersson-Rosenthal Syndrome
  11. Strawberry gingivitis
    Wegener's Granulomatosis
  12. Subepithelial split at BM, IgG and C3
  13. Abs against collagen VII
    Epidemolysis Bullosa Acquisita
  14. IgA Abs
    Linear IgA
  15. DSG3
    Pemphigus Vulgaris
  16. Tzanck cells
    Pemphigus Vulgaris
  17. Fishnet appearance on IF
    Pemphigus Vulgaris
  18. Patient already diagnosed with cancer
    Paraneoplastic Pemphigus
  19. DSG1, subcorneal split
    Pemphigus Follaceus
  20. Wickham's Striae
    Reticular LP
  21. Hyperkeratotic , leukoplakic, raised or flat on tongue and buccal mucosa
    Plaque Form LP
  22. Looks like MMP, but has white striae and is precancerous
    Erosive LP
  23. Large bullae rupture and cause erosion
    Bullous LP
  24. Erosions and white striae around amalgam
    Lichenoid reaction
  25. LP invades the nerve
  26. Band of T lymphocytes around BM, thickening of BM, degeneration of basal cells, antifibrinogen Ab
    Lichen Planus
  27. Topical tx that is not a steroid (good for DM and HTN pts)
  28. Malar rash, photosensitivity
    Lupus Erythematosis
  29. ANA+, dsDNA+, anti-smith Abs
    Lupus Erythematosis
  30. Brown tumor
  31. Vitamin D deficiency in children
  32. Vitamin D deficiency in adults
  33. Increased osteoid, decreased mature bone
  34. Deficiency of bone tissue per unit volume of bone, treat with bisphosphonates
  35. Giantism and acromegaly
  36. "hair on end"-- radial striations in the diploic space of the skull
    Sickle cell anemia/thalassemia
  37. Bilateral uncontrolled growth of bone w/ cement lines
    Paget's Disease
  38. Bilateral uncontrolled growth of bone w/ cement lines
    Paget's Disease
  39. Sclerodactyly, widening of PDL space, Reynaud's syndrome
  40. Enlarged Langerhan's cells, eosinophils and "floating teeth"
    Langerhan's cell histiocytosis
  41. Acute Disseminated LCH
    Letter-siwe disease
  42. Bone lesions, diabetes insipidus and exophthalmos Hand-Schuller-Christiansen Triad=
    Multifocal LCH
  43. PTCH mutation
    Gorlin syndrome
  44. Multiple OKCs and basal cell carcinomas
    • Gorlin syndrome (nevoid basal cell carcinoma syndrome)
    • Palmar and plantar pits
    • Skeletal abnormalities
    • – Intracranial calcification
    • – Rib and vertebral anomalies
    • • Characteristic face:
    • – Enlarged head circumference (frontalbossing)
    • – Hypertelorism
    • • Various types of tumors (<15%)
  45. variation in allelic expression when the allele is penetrant.
  46. frequency of expression of an allele when it is present in the genotype of the organism
  47. RET mutation
  48. Marfanoid body build
    oral mucosal neuromas
    medullary carincoma of the thyroid pheochromocytoma
  49. APC mutation
    Gardner Syndrome
  50. Multiple osteomas, impacted teeth, odontomas, 100% develop colorectal carcinoma, supernumary teeth
    Gardner Syndrome
  51. STK11 mutation
    Peutz-Jeghers Syndrome
  52. Benign (hamartomatous) polyps,
    freckle-like spots on perioral skin and hands)
    Peutz-Jeghers syndrome
  53. NF1 mutation
    Neurofibromatosis Type 1
  54. Café au lait spots
    crowe's sign(axillary freckling)
    lisch nodules (iris)
    multiple neurofibromas
    Neurofibromatosis type 1
  55. Port wine stains along CN V
    leptomeningeal angiomas
    Sturge-Weber Angiomatosis
  56. touch nose w/ tongue
    gorlin sign: ehlers-danlos
  57. Hypermobility of joints, elastic skin, gorlin sign
    Ehlers-Danlos Syndrome
  58. multiple vessel abnormalities->exessive bleeding
    multiple papules
    recurrent epistaxis
    AV malformations
    Hereditary Hemorrhagic Telangiectasia
  59. Red papules, family hx, epistaxis, AV-malformation Hereditary hemorrhagic Telangiectasias,Peg-shaped incisors, heat intolerance (can't sweat)
    Ectodermal Dysplasia
  60. RUNX2 (CBFA1) mutation
    • Cleidocranial Dysplasia
    • RUNX2 (CBFA1) osteoblast & odontoblast development
  61. Hypoplastic clavicle, delayed eruption of permanent teeth
    Cleidocranial Dysplasia
  62. Café au lait spots, sexual precocity, fibrous dysplasia
    McCune-Albright Syndrome
  63. Fe deficiency + glossitis + dysphagia (esophageal webs)
    • Plummer-Vinson Syndrome
    • tx: Fe supplement
  64. Facial paralysis, swollen lips (OFG), fissured tongue
    Melkerson-Rosenthal Syndrome
  65. Esophageal webs
    Plummer-Vinson Syndrome
  66. Erosion, osteophytes, subchondral sclerosis
  67. Inherited skin condition with no other allergic conditions
    Atopic dermatitis
  68. Scratching leads to excoriations
  69. Itchy skin rash→ begins hours after contact
    Allergic contact dermatitis
  70. Excessive contact with irritatnts, causes hand dermatitis
    Irritant Contact Dermatitis
  71. Increased skin cell turnover with slow shedding
  72. Auspitz's sign
  73. Histamine causes angioedema of lips and hands
  74. Abnormal C1NH protein
    Angioedema (w/out urticaria)
  75. Tongue blade test Physical urticaria
  76. P. Acnes
  77. Affects areas exposed to sunlight over a long period of time, solar elastosis also involved
    Solar comedones
  78. Migraine headaches, sun damage, erythema, telangiectasia
  79. Mixed population of staph and strep
  80. Collection of pus in a firm mass caused by S. aureous
  81. Survive in dead keratin
    Dermatophyte infections
  82. Athlete's foot
    Tinea pedis
  83. Jock itch
    Tinea cruris
  84. Ringworm
    Tinea corpuris
  85. Ringworm of the scalp
    Tinea capitus
  86. Burrow into skin
  87. Do NOT burrow, transmitted by combs
    Pediculosis (lice)
  88. Larvae enter swimmer's pores and die
    Swimmer's Itch
  89. Increased epithelial turnover rate
  90. Hair loss from crash diets
    Telogen effluvium
  91. Abrupt hair loss from chemo
    Anagen effluvium
  92. Patchy hair loss from autoimmune condition
    Alopecia areata
  93. Jellyfish and coral stinging structures
  94. Antimicrobial anti-HIV components of saliva
    HIV-specific IgA, SLIPI
  95. Dark pink submucosal swelling
    Lymphoid hyperplasia
  96. Normal low PMN counts
    Benign ethnic neutropenia
  97. Absence of PMNs, caused by anticancer chemotherapeutic agents
  98. Periodic reduction in PMN population
    Cyclic neutropenia
  99. Decreased production, increased destruction, sequestration in spleen
  100. Increase in mass of RBCs→TIA, CVA, MI
    Polycythemia Vera
  101. Scooped out mandible, floating teeth, large langerhan's cells
    Langerhan's cell histiocytosis
  102. Blast transformation, 9/22 translocation
  103. Reed-sternberg cells
    Hodgkin's Lymphoma
  104. Owl-eye nucleus
    Hodgkin's lymphoma
  105. B-lymphocytes affected, MALT formation
    Non-Hodgkin's Lymphoma
  106. Cells have minimal cytoplasm
    Non-Hodgkin's Lymphoma
  107. "starry sky" appearance
    Burkitt's Lyphoma
  108. Kids, posterior jaws, multiple quadrants affected
    Burkitt's Lymphoma
  109. B-lymphocyte malignancy associated with EBV
    Endemic Burkitt's Lymphoma
  110. Bence-Jones protein, amyloid deposition
    Multiple myeloma
  111. Eccentric nuclei, stippled nuclear chromatin
    Multiple myeloma
  112. Plasma cell origin, Punched out lesions on radiograph
    Multiple myeloma
  113. Glossitis, angular cheilitis, koilonychias, splenomegaly
  114. VIII-A and IX-B deficiency
  115. Impaired collagen synthesis results in bleeding gums
    Vitamin C deficiency/Scurvy
  116. White, creamy, removable plaques
    Pseudomembranous oral candidiasis (thrush)
  117. Elongated hyphae, thigmotropism
    Oral candidiasis
  118. Diagnosed using periodic acid Schiff
    Oral candidiasis
  119. Treated with Amphotericin B
    Deep Mycoses
  120. Leads to CNS involvement
  121. Cough, anemia, shiny papules, 3rd most common
  122. Reactivation of latent infection, fever, weight loss
  123. Causes sinus infection and invasive lesions
  124. Viscera, lymph nodes, mucocutanous tissues affected
  125. Pulmonary infection and erythema multiforme
  126. Erythematous linear banding, not related to plaque
    Linear gingival erythema
  127. Destruction of one or more interdental papillae
  128. Loss of periodontal attachment and bone
  129. Ulcers on non-keratinized mucosa
    Aphthous ulcers
  130. Ulcers on keratinized mucosa
  131. In HIV, will cross onto the "wet" lip
  132. Stops at midline along one dermatome
    Herpes zoster
  133. NO langerhan's cells, chromatin margination, EBV
    Oral hairy leukoplakia
  134. HPV-related lesions Verruca vulgaris, condyloma acuminatum, focal epithelial hyperplasia HHV-8, cancer of lymphatic endothelium and forms bloodfilled vascular channels
    Kaposi's Sarcoma
  135. HIV increases risk by 60x
    Non-hodgekin's lymphoma
  136. HIV-related salivary gland disease Sjogren-like syndrome, diffuse CD8 lymphocytic infiltration (DILS), lymphoepithelial cysts of salivary glands, malignant lymphoma Improving immune system reduces Tregs and worsens clinical symptoms
    • xanthelasma
    • yellow papules(cholesterol)
  137. Arcus Senilis
  138. Pterygium
  139. Pingecula
  140. Carbuncle (aggregate of connected furuncles)
  141. large, bulbous, ruddy nose caused by granulomatous infiltration, commonly due to untreated rosacea