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Define Typhoid Fever
An acute enteric infectious disease caused by Salmonella typhi (S.Typhi). The lesions occur in the lymphatics of the terminal ileum. Here there is proliferation of large mononuclear cells derived from the mononuclear phagocyte system (MPS) which leads to sustained fever, relative bradycardia, apathetic facial features, roseola, splenomegaly, hepatomegaly, leukopenia, intestinal hemorrhage, and intestinal perforation
What are the 4 serotypes of salmonella that cause enteric fever?
- Salmonella paratyphi A (Serogroup A)
- Salmonella paratyphi B (Serogroup B)
- Salmonella Choleraesuis (Serogroup C)
- Salmonella typhi (Serogroup D)
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