Antiemetic and Antinausea drugs

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Author:
WindWell2794
ID:
208100
Filename:
Antiemetic and Antinausea drugs
Updated:
2013-03-18 19:58:17
Tags:
Pharm test four
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Description:
Pharm test four
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  1. Anticholinergic drugs Mechanism of action
    block transmission of nauseating stimuli to CTZ
  2. Antihistamines Mechanism of Action
    • inhibit ACh by binding to H1 receptors¬†
    • prevent cholinergic stimulation in vestibular and reticular areas
  3. Antidopaminergic drugs Mechanism of Action
    block dopamine receptors in the CTZ
  4. Prokinetic drugs Mechanism of Action
    • block dopamine receptors in the CTZ
    • causes CTZ to be desensitized to impulse it receives from the GI tract
  5. Serotonin blockers
    block serotonin receptors located in the GI tract, CTZ, and vomiting center
  6. Tetrahydrocannabinol (THC)
    inhibit effects on reticular formation, thalamus, cerebral cortex
  7. Ginger adverse effects
    nausea and vomiting, anorexia, skin reaction

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