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- Attaches to toxin/substance in proximity of GI tract.
- Toxic Ingestion
- Ingestion of acids, alkalis, ethanol, methanol, cyanide, ferrous sulfate or other iron salts, lithium; coma; GI obstruction.
- *Side effects:
- NVD, constipation, potentially fatal pnuemonitis if aspirated.
- A: 50-100 g PO
- P:1 to 2 g/kg PO
Preg class C.
- Slows conduction of electrical impulses at the AV node.
- Stable reentry SVT's. Will not convert AFib, A Flutter, or VT.
- Sick sinus syndrome, 2nd or 3rd degree block, poison/drug induced tachycardias.
- A: Initial dose 6 mg rapid IV/IO push followed by 20cc NS blous. Repeat a 12 mg, and once more at 12 mg if needed.
- P: > 50kg adult dosing
- < 50kg Initial dose of 0.1 mg/kg IV/IO to max dose of 6 mg followed by 5 cc NS bolus. May repeat at 0.2 mg/kg to max of 12 mg.
- *Side Effects:
- Sense of impending doom, flushing, chest pressure, throat tightness, numbness, Brief period of asystole.
Bronchodialtor, beta agonist
- Binds to and stimulates beta2 receptors for relaxation of bronchial smooth muscle.
- *Indications: Asthma, bronchitis with bronchospasm, and COPD.
- *Contraindications: Angioedema, sensitivity to albuterol or levalbuterol. Use with caution in lactating Pt's, cardiovascular disorders, and arrythmias.
- A: 2.5 Mg in 3ml by neb every 20 min to max of 3. Continuous neb 10-15 mg/hr.
- P: > 12 yrs, Continuous neb 0.5 mg/kg/hr
- < 12 yrs, 0.15 mg/kg/hr
- *Side effects:
- Hyperglycemia, hypokalemia, palpitations, sinus tach, anxiety, tremors, N/V, throat irritation, dry mouth, HTN, dyspepsia, insomnia, HA, epistaxis, paradoxical bronchospam.
Antiarrythmic Class III
- *Action: Acts directly on myocardium to delay repolarization and increase duration of the action potential.
- *Indications: Ventricular arrythmias, second line agent for atrial arrythmias.
- *Contraindications: Sick sinus syndrome, 2nd and 3rd degree HB, cardiogenic shock, episodes of bradycardia resulting in syncope, sensitivity to benzyl alcohol and iodine.
- *Dosage: Adult Arrest- 300 mg IV/IO, repeated in 3-5 min at 150 mg. Must be diluted with NS.
- Peds Arrest-5mg/kg IV/IO (max dose of 300mg), may repeat 5mg/kg up to 15 mg/kg.
- Wide complex tach- A: 150 mg in 100mL D5W over 10 min, may repeat, max dose of 2.2 g over 24hrs.
- P: 5mg/kg slowly over 20-60 min, may repeat up to 15mg/kg (max dose 300mg)
*Side Effects: Burning at IV site, hypotension, bradycardia.
Antiplatelet, Nonnarcotic analgesic, Antipyretic
- *Action: Inhibits the production of thromboxane A2, reducing platelet aggregation.
- *Indications: Fever, inflammation, angina, acute MI, chest pain/pressure that may be of cardiac origin.
- *Contraindications: GI bleed, active ulcer disease, hemorrhagic stroke, bleeding disorders, children with chicken pox or flu like symptoms, known sensitivity.
- * Dosage: Adult MI 160-325 mg PO, 300 mg rectal suppository. Ped MI 3 to 5 mg/kg/day to 10 mg/kg/day given as a single dose.
- Adult Pain/Fever 325 to 650 mg PO every 4-6 hrs. Peds Pain/Fever 60 to 90 mg/kg/day in divided doses every 4-6 hours.
*Side effects: Anaphylaxis, angioedema, bronchospasm, bleeding, stomach irritation, N/V.