Describe what happens in the Loop of Henle. Include Facultative Reabsorption.
1) As you ascend you actively transport chloride
out into the tissue
2) Ascending limb has a special property relative to water (it's impermeable
3) Sodium chloride is pumped out of tissues and the filtrate will follow the solute out into the tissue. The wall blocks the water.
4) Exchanger Effective - Vasa Recta
--> looping capillaries parallaling will complement the multiplier by having blood descend and pick up the increasing solute concentration going into the vessel. Diffusion can also drop solute concentration off. Now solutes are deep in medulllary tissues (recycling
5) Modulator - ADH
(anti-diuretic hormone) is invoked. When circulating it has one function - open the walls of the collecting ducts to water to create aquaphorine channels. (if ADH is up, urine output will be decreased and vice versa)
Alcohol blocks your ADH - making your collecting ducts closed causing dehydration.