Malaria

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Author:
aeldavies
ID:
210098
Filename:
Malaria
Updated:
2013-03-28 22:14:49
Tags:
Pathology malaria
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Description:
quick overview of malaria
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  1. Malaria classification
    • Family-Protozoa
    • Class-Sporozoa (sexual reproduction, some binary fission)
    • Genus-Plasmodium
    • Species- falciparum, vivax, ovale, malariae

    • definitive host: mosquito
    • Intermediate host- humans (monkeys and other animals)
  2. Plasmodium falciparum
    • Tropics
    • Host resistant to sickle cell
    • attacks RBCs
    • High death rate and severity of attack
    • Multiple merozoites in RBC
    • Double chromatin dots
    • Banana shaped gametocyte
  3. Plasmodium vivax
    • Tropics/subtropics
    • Resistant to duffy antigen receptor negative
    • Young RBCs (reticulocytes)
    • Latent infection
    • Large RBCs
    • Schuffner's dots
    • All forms of life cycle in peripheral blood
    • Amoeboid gametocyte
  4. Plasmodium ovale
    • Africa
    • Young RBCs (reticulocytes)
    • latent infection
    • Large RBCs
    • Schuffner's dots
    • All forms of life cycle in peripheral blood
    • Amoeboid gametocyte
  5. Plasmodium malariae
    • Subtropics
    • Old RBCs
    • Chronic persistence
    • All forms of life cycle in peripheral blood
    • Amoeboid gametocyte
  6. Vaccination
    none
  7. Precautions
    • Screen houses
    • Netting over beds
    • Clothing
    • Insect repellent (DEET)
    • Insectacides
  8. Prophylactic medication
    • Malarone
    • Mefloquine
    • Doxycycline
    • Chloroquine + proguanil
    • Chloroquine

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