gi drugs

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Author:
bpayton
ID:
210314
Filename:
gi drugs
Updated:
2013-03-30 03:13:35
Tags:
pharm
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Description:
GI drugs
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  1. What are 3 gastric cells that are involved in gastric acid production?
    parietal, chief, and mucous cells
  2. what do parietal cells do?
    produces and secretes HCL acid
  3. What do chief cells do?
    • Secretes pepsinogen
    • converts pepsinogen into pepsin in the acidic gastric environment
  4. What do mucous cells do?
    • Secretes mucous
    • Vital in maintaining the protective gastric mucosa lining
  5. What is the mechanism of the action of antacids?
    • Antacids:
    • used to neutralize gastric acid
    • promotes gastric mucosal defenses
  6. What are antacids made up of?
    • Aluminum
    • Magnesium
    • Calcium
    • Sodium
  7. What are the reasons for Antacids?
    • Treat symptoms of:
    • PUD
    • Gastritis
    • Gastric Hyperacidity
    • Heartburn
  8. What type of people should not take antacids?
    Patients with renal insufficiency
  9. What are the overall side effects of antacids?
    • Alkalosis
    • Mask symptoms of other disease
  10. What is the side effect of antacids with magnesium?
    Diarrhea
  11. What is the side effect of antacids with aluminum?
    • Constipation
    • Hypercalcemia
    • Hypophosphatemia
  12. What is the side effect of antacids with Calcium?
    • Constipation
    • kidney stones
    • rebound hyperacidity

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