How does the sex of an individual affect the mutation rate in the germline?
Male gametes are constantly produced throughout the life of a male, while female gametes are produced only once in the beginning of life, then stored. Mutations can accumulate in female gametes. However, such mutations can also cause the egg to not be released, or to malfunction. Female gametes are more susceptible to mutations that prevent the formation of a zygote than male gametes.