If mother is Rh-, should recieve Rh immune globulin(RhoGAM) at 28 wk's gestation.
RhoGAM promotes lysis of fetal Rh+ RBCs circulating in maternal bloodstream before Rh- mother develops her own antibodies to them.
- Mom Rh- =no Antigen
- Dad Rh+ = has Rh Antigen
Baby Rh+ = has Rh Antigen, mother's body could create antibodies to attack Rh Antigen in baby's blood. RhoGAM kills Rh antigens in mother's blood stream before mother can develop antibodies.