PTG 105 - Exam 3 -Lecture 15-2
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. What would you like to do?
- Failure of LES (lower esophogeal sphincter) to open and allow the passage of food into the stomach.
- Due to a neural input defect.
What are the symptoms of Achalasia?
- Chest pain
Complication of Achalasia are:
- Aspiration of food into the lungs
- increased risk of squamous cell carcinoma of the esophogous
Which esophogeal disease is characterized by incresaed tone in the LES due to a neural defect?
Dysphagia, Vomiting and Chest pain are symptomatic of what esophogeal disease?
Describe Mallory Weiss syndrome:
Tear in the esophogous at the Gastroesophogeal junction
Mallory Weiss syndrome is often caused by:
Chronic alcohol consumption and vomiting.
Symptoms of Mallory Weiss syndrome are:
Upper GI bleeding
Upper GI bleeding is symptomatic of what alcohol induced esophogeal disease?
Mallory Weiss Syndrome
A dangerous disease that causes dialated blood vessels in the esophageal wall is:
What is the etiology of Esophogeal Varicies?
- portal hypertension
- cirrhosis of the liver
What percentage of people die from catastrophic hemmorhage of esophogeal varacies?
portal hypertensiona nd cirrhosis of the liver cause what esophogeal disease?
What is the treatment for Esophageal Varacies?
Endoscopic sclerotherapy is the treatment for what disease?
What is Refulx Esophagitis?
incompetent LES allows gastric acid to fluctuate from the stomach to the esophagous
The flow of gastric juices to the esophagous is what disease?
What are common causes of reflux esophagitis?
- Hiatal Hernia
Obeisity Pregnancy and Hiatal Hernia can cause what disease?
What are late symptoms of reflux esophagitis?
What is the pathogenisis of reflux esophagitis?
- eventually: metaplasia or Barrett's esophagous
What are long term developments of reflux esophagitis?
- Barrett's esophagous
How does reflux esophagitis manifest itself?
- Hemmorhage with ulcers
- Dysphagia with stricture
What characteristic cells are found in the esophogous with reflux esophagitis?
Eosinophils (+ or - neutrophils)
Where are eosinophils and (maybe) neutrophils found during reflux esophagitis?
In the esophageal epithelium
chronic liver disease marked by degeneration of cells, inflammation, and fibrous thickening of tissue
Epigastric pain from reflux esophagitis can mimic what other serious condition?
Erroded mucosa of the esophagus near the gastroesophageal junction is indicative of what disease?
What are the treatment options for relux esophagitis?
- Food avoidance
A Candida Infection can cause what disease?
Esophagitis can be caused by what bacteria?
How do you distinguish a Candida caused esophagitis from other esophatitis etiologies?
Plaque seen on the esophageal tissue
Multinucleated cell in the esophogous indicated what disease?
The nucleii of multinucleated esophogeal cells associated with Herpes esophagitis contain what?
What symptoms are indicative of Herpes esophagitis?
- Ulcer formationin the esophagitis
- Multinucleated cells in the esopagous
What type of metaplasia is indicative of Barrett's esophagus?
What type of mucosa cells line a normal esophagus?
Squamous cell muscosa
Describe the basic pathogenisi of Barrett's Esophagus:
Squamous cell mucosa of the esophagous is replaced with intestinal type mucosa containing goblet cells.
When intestinal type mucosa becomes metaplastic and is converted to intestinal type mucosa containing Gobelt cells, what disesae is indicated?
BE stands for what?
Barrett's esophagous is a complication of what disease?
GERD = gastroesophageal Reflux Disease
What condition is premalignant and leads to adenocarcinoma of the esophagus and gastroesophageal junction?
What is a complication of Barrett's Esophagus?
premalignancy that can lead to adenocarcinoma of the Esophagus and Gastroesophageal Junction.
Describe how Barrett's Esophagus develops?
Gastric acid in the esophagus causes mucosal inflammation and prolonged injury results in Barrett's esophagus
What is a formal description of what changes occurs in Barrett's Esophagus?
What would you like to do?
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