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  1. Amnesia
    Amnesia
  2. Amnesia preceded by epigastric sensation and fear are associated with electrical abnormality where?
    Temporal lobe
  3. Memory loss pattern in dissociative amnesia
    Memory loss occurs for a discrete period of time
  4. Amnesia characterized by loss of memory of events that occur after onset of etiologic condition or agent
    Anterograde
  5. What psychoactive drug produces amnesia?
    Alcohol
  6. Brain Lesions
    Brain Lesions
  7. Visual problem in pituitary tumor compressing optic chiasm
    Bitemporal Hemianopsia
  8. "32 y/o pt 1-month history of worsening headaches
    episodic mood swings and occasional hallucinations with visual
  9. "Syndrome characterized by fluent speech
    preserved comprehension
  10. Acute onset of hemiballismus of LUE & LLE. MRI is most likely to show lesion located where?
    Subthalamic nucleus
  11. Left sided hemi-neglect is associated with lesion located where?
    Right Parietal Lobe
  12. "60M right-handed
    getting lost
  13. Which hormone secreted in functional pituitary adenoma:
    Prolactin
  14. CT & MRI show ventriculomegaly are out of proportion to sulcal atrophy. This is suggestive of what diagnosis?
    Normal Pressure Hydrocephalus
  15. "5 y/o with 4 month history of morning HA
    vomiting
  16. "20 y/o with 1 yr of bitemporal headaches
    polydipsia
  17. Previously pleasant mom becomes profane and irresponsible over 6 months:
    Frontal lobe
  18. "Unilateral hearing loss with vertigo
    unsteadiness with falls and headaches
  19. Catatonia
    Catatonia
  20. "52 y/o with h/o unipolar depression is brought to ED with a first episode of catatonia. Patient is on no meds
    UDS is neg. Further w/u should initially focus on what factor?"
  21. Which term describes state of immobility that is constantly maintained?
    Cataplexy
  22. Ability of catatonic pt to hold same position
    Catalepsy
  23. Obsessive-compulsive symptoms are characterized by which defense mechanism?
    Isolation and undoing
  24. CVA
    CVA
  25. "Chronic Afib develops aphasia and R hemiparesis at noon. ER exam notes weakness of R extremities and severe dysfluent aphasia
    but CT at 1:30 PM has no acute lesion. Most appropriate treatment:"
  26. Young adult gained 70 lbs in last year c/o daily severe headaches sometimes assoc with graying out of vision. Papilledema present. CT and MRI brain no abnormalities but ventricles smaller than usual. Goal of treatment in this case:
    Prevent blindness
  27. "Patient with hypertension develops vertigo
    nausea
  28. "Rapid onset of right facial weakness
    left limb weakness
  29. Transient symptom associated with carotid stenosis: ***
    Monocular blindness
  30. "62 y/o M w DM is not making sense
    saying ?thar szing is phrumper zu stalking?. Normal intonation but no one in the family can understand it. He verbally responds to questions with similar utterances but fails to successfully execute any instruction. ****"
  31. "58 y/o M h/o HTN
    cig smoking and sudden inability to speak. Face drooping on R and dragging R leg. In ER examined within 40 mins of onset: Aphasic
  32. Abulia refers to impairment in ability to:
    Spontaneously move and speak
  33. Sudden-onset left hemiparesis with deviation of eyes to the right
    Right putaminal hemorrhage
  34. "Sudden onset vertigo/nausea
    hoarseness/dysphagia
  35. "65 y/o diabetic presents to ED c/o acute L sided weakness
    deviation of gaze to R
  36. "Pt with acute onset vertigo
    what will suggest R lateral medullary infarct?"
  37. "46 y/o M w/ double vision + pain R eye. Exam: ptosis R eyelid
    inability to elevate or adduct R eye + R pupillary dilation. This is caused by:"
  38. "Aphasia w/ effortful fragmented
    dysfluent
  39. 39 year old with h/o of multiple miscarriages develops an acute left sided hemiparesis. Work up revels elevated anticardiolipin titers and no other risk factors for stroke. Appropriate intervention at this point is?
    Plasmapheresis
  40. Abnormal elevated metabolic findings associated with increased risk of stroke in patients under 50
    Plasma homocysteine
  41. "73 y/o found on floor
    unaware of L UE/LE. Flaccid L arm
  42. CT scan with occipital and intraventricular hyperintensities
    Parenchymal hemorrhage
  43. Which med has secondary prevention against embolic stroke in patients with Afib?
    Oral warfarin
  44. "As opposed to strokes caused by arterial embolism or thrombosis
    those caused by cerebral vein or venous sinus thrombosis are"
  45. Atrophy of right temporal lobe on cross section associated with occlusion of:
    Middle cerebral artery
  46. "Loss of ability to execute previously learned motor activities (which is not the result of demonstrable weakness
    ataxia or sensory loss) is associated with lesions of?"
  47. "58 y/o s/p CABG ? anomia for fingers and body parts
    errors involving right and left
  48. Visual disturbances associated with occlusion of the right posterior cerebral artery?
    Left homonymous hemianopsia
  49. "65 y/o with HTN collapsed. In ED is stuporous
    R hemiparesis + hemisensory deficit
  50. Higher frequency & greater severity of depression associated w/ cortical & subcortical strokes
    Left anterior frontal
  51. Pt with hypertension develops painless vision loss on the left eye. PE revels blindness in the left eye and afferent papillary defect on the left. MRI shows several T2 hyperintensities in the white matter periventricularly. No corpus callosum lesions. No enhancement with gadolinium. Dx?
    Ischemic optic neuropathy
  52. "63 y/o with new onset aphasia and R hemiparesis
    2 days ago had milder/similar symptoms that resolved in 30 minutes
  53. Lower facial weakness w/ relative sparing of forehead can be stroke in
    Internal capsule
  54. Prosopagnosia is:
    Inability to recognize faces
  55. "57 y/o diabetic w/ HTN c/o several episodes of visual loss ?curtain falling? over his L eye
    transient speech and language disturbance
  56. Head injury with LOC followed by lucid interval for a few hours then rapidly progressing coma. What hemorrhage?
    Epidural
  57. 5 days after CABG a 47 yr M is disoriented in time and place. He identifies his right and left but not that of the examiners. Can draw square and circle but not a clock. This is:
    Dyspraxia
  58. "Pt in ED with sudden HA and collapsing
    some lethargy. Exam shows rigid neck
  59. Post stroke depression in an 80 y/o pt who is R handed is associated with cognitive impairments that
    Correlate with left hemispheric involvement
  60. Fluent speech with preserved comprehension but inability to repeat statements is consistent with what type of aphasia?
    Conduction
  61. Normal Romberg w eyes open but loses balance with eyes closed. Where is abnormality?
    Cerebellar vermis
  62. "65 y/o with h/o HTN
    Meniere?s with sudden vertigo
  63. "66 y/o M in ED w/ sudden occipital HA
    dizziness
  64. Motor speech paradigm activation task on fMRI ? hyperactivity in right temporal lobe. Damage is where?
    Calcarine fissure
  65. Inability to recognize objects by touch:
    Astereognosis
  66. "In managing acute ischemic stroke
    administer this within 48 hrs of onset of stroke for beneficial effect in reducing risk of recurrent stroke
  67. "70 y/o w/ attacks of ?whirling sensations? w/n/v
    diplopia
  68. Component of type A behavior most reliable risk factor for CAD
    Hostility
  69. "70 y/o F sudden onset paralysis R foot and leg. R arm and hand lightly affected. No aphasia or visual field deficit. Over weeks found with loss bladder control
    abulia and lack of spontaneity. Which vascular area:"
  70. Complications of a cerebellar hemorrhage?
    Acute hydrocephalus
  71. Delirium
    Delirium
  72. Multifocal myoclonus in a comatose patient indicates:
    Metabolic Encephalopathy
  73. "50M male w/ progressive dementia
    ataxia
  74. "79 y/o with decreasing mental state over 3 weeks has an exaggerated startle response with violent myoclonus that is elicited by turning on the room lights
    speaking loudly
  75. "Two days after bowel surgery
    53 y/o is delirious. Correctly draws a square when asked
  76. "75 y/o F is 8 days s/p total hip replacement and has delirium. Her diazepam and doxepin were discontinued just prior to surgery. She is getting meperidine for pain
    diphenhydramine for sleep and a renewed prescription for doxepin. Her confusion is likely due to: medication toxicity
  77. "Best recommendation for pt with delirium? Minimize contact with family members or limit sleep meds to diphenhydramine
    or maximize staff continuity assigned to pt?"
  78. Delirium in HIV patients treated with what parental agent?
    Low dose of a high-potency antipsychotic
  79. "Mild confusion
    lethargy
  80. "Cancer patient on chemo is disoriented and agitated. Afebrile VSS. Neg neuro exam. Poor attention
    cog impairment. Held for observation. CT neg
  81. "A 70 y/o +HIV heroin abuser is treated with Lopinavir and Ritonavir and fluoxetine for MDD. Hep C was dx and treated 2 months ago. Since then pt is more irritable
    insomnia
  82. "A consult is requested for an inpatient on a medical ward who is agitated and hallucinating. Pt appears to be flushed and hot with dry skin
    mydriasis
  83. "52 y/o w/ depression and HTN
    severe headaches
  84. Suggests delirium rather than dementia
    Clouding of consciousness
  85. Dementia
    Dementia
  86. "65 y/o M 6 months confusion episodes
    disorientation
  87. "Dementing illness with limb and axial rigidity tremor
    fluctuations in cognitive function
  88. "70 y/o woman has dementia
    abnormal proprioception
  89. "74F PI
    suspicious
  90. "Safest heterocyclic antidepressant for a 78 y/o with depression
    agitation and dementia is:"
  91. What cognitive enhancers is an NMDA receptor antagonist?
    Memantine
  92. Neuronal damage from excitotoxicity secondary to glutamate sensitivity. Treat with:
    Memantine
  93. "75 y/o with mild intermittent forgetfulness
    hallucinations
  94. Detection of 2 Apolien e4 alleles is useful in dx dementia b/c
    Increases probability of dx of Alzheimers
  95. Neurofibrillary tangles in Alzheimer?s are composed of:
    Hyperphosphorylated tau proteins
  96. 80 y/o Alzheimer?s with increasingly combative behavior. Family wants to keep at home. Give what med?
    Haldol
  97. "Dementia characterized by personality change
    attention deficits
  98. Alzheimer?s disease risk ? Apolipoprotein E phenotype
    ?4?4
  99. "Binswanger disease has pseudobulbar state
    gait disorder
  100. An 80yo pt with Alzheimer?s is brought in for increasingly combative behavior. Daughter would like to keep the pt at home if possible. What interventions would be most helpful in this situation?
    Assessing for caregiver burnout
  101. Which meds have best results for treating agitation in dementia?
    Anti-psychotics
  102. Clock drawing test is quickly administered and sensitive screen for which d/o?
    Alzheimer?s
  103. Amyloid precursor protein in
    Alzheimer?s Disease
  104. Most common cause of dementia:
    Alzheimer?s disease
  105. Individuals over 40yo with Down?s syndrome frequently develops:
    Alzheimer?s
  106. What baseline labs should be taken before starting tacrine?
    ALT and AST (baseline and f/u)
  107. Known risk factors for dementia:
    "Age
  108. Neuronal enzyme that is the target of drugs to treat Alzheimer?s i.e. galantamine and rivastigmine
    Acetyl cholinesterase
  109. Seizures
    SZ
  110. "19 yr old woman has bouts of motor agitation
    often followed by intense
  111. Which procedure confirms the diagnosis of non-epileptic seizures? Video telemetry or EEG between episodes?
    Video telemetry (CL: Should be more accurately called EEG Video telemetry)
  112. Antiepileptic for juvenile myoclonic epilepsy
    Valproic Acid
  113. Complex partial seizures are differentiated from simple partial seizures by:
    Simple seizures have no loss of consciousness but have altered responsiveness to outside stimuli.
  114. "Convulsive episode with leftward eye deviation
    tonic contracture of left side. Postictally
  115. "28 female w/ HA
    hyperventilates
  116. "In young pt w/ epilepsy
    tx depression w/"
  117. Lack of prolactin elevation after szs suggests what kind of szs:
    Non-epileptic
  118. "32 y/o with partial complex seizures refractory to treatment
    picture of MRI shown. (picture)"
  119. Drug-addicted healthcare professional experiences seizure that is not a withdrawal phenomenon. Cause?
    Meperidine
  120. What is the diagnostic value of transient paresis or aphasia after a seizure?
    Localizes the focus of seizure
  121. Complex partial epilepsy aura has what symptom?
    Lip smacking
  122. Head & eyes deviate to right and right arm extends immediately before a generalized tonic-clonic seizure
    Left cerebral hemisphere
  123. Gustatory special sensory seizures (auras) localize where?
    Insular cortex
  124. First sz with focal onset and second generalization in a 58 y/o patient is most likely the consequence of what?
    Glioblastoma multiforme
  125. "10 y/o child freq episodes brief lapses of consciousness without premonitory sxs. Lasts 2-10 seconds
    followed by immediate and full resumption of consciousness without awareness of what has happened. These ictal episodes most likely caused by what kind szs:"

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