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kyleannkelsey
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What is the term for abnormal bleeding in the uterus without a lesion?
Dysfunctional uterine bleeding
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What is the definition of Dysfunctional uterine bleedsing?
Ueterine bleeding sans lesion
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Edometrial biopsy can be used to test for Dysfunctional uterine bleeding (T/F)?
False, it does not show the disease
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Why does Dysfunctional uterine bleeding occur?
Hormonal changes
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Hormonal changes can cause what uterine disease?
Dysfunctional uterine bleeding
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What test is not useful in testing for dysfunctional uterine bleeding?
Endometrial biopsy
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Edometrial polyps are usually cancerous (T/F)?
False, they are usually benign
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What re the symptoms of Endometrial polps?
- Intermestrual bleeding
- Menorhagia
- Postmenstrual bleeding
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What dises is indicated by postmenstrual bleeding, Menorrhagia and Intermenstrual bleeding?
Endometrial polyps
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Tamoxifen is used for what?
Treatment of breast cancer
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What are endometrial polyps associated with?
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Tamoxifen and Heperestrinism are associated with what disease?
Endometrial polyps
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Describe endometrial glands in a pateint that has endometrial polyps:
Normal architecture or cystically dialated
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What is Leiomyoma?
Common benign tumor of the female reproductive tract smooth muscle
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How common are Lieomyomas?
30-50% of women will develop in their reproductive life
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30-50% of women will develop what disease during their reproductive life?
Leiomyoma
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What is the etiology of Leiomyoma?
Genetics, Estrogen and OCP
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What are the symptoms of Leiomyoma?
- Asymptomatic
- Miscarraige
- Pressure symptoms
- Menorrhagia
- pain
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What female urogenital disease has teh following manifestations:
Asymptomatic, pain, menorrhagia, pressure symptoms, miscarriage?
Leiomyoma
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What is the term for a malignant tumor of the uterine smooth muscle?
Leiomyosarcoma
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What is Leiomyosarcoma?
Malignant tumor of the uterine smooth muscle
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What are the manifestations of Leiomyosarcoma?
Cellular atypia, nuclear pleomorphism, increased mitotic activity and necrosis
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What disease is indicated by the following manifestations: Nuclear pleomorphism, necrosis, increased mitotic rate and cellular atypia?
Leiomyosarcoma
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What does a Leiomyoma look like grossly?
Well defined rubbery mass with "whorled out" cut surface
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A well defined rubbery mass with a "whorled out" cut surface is likely what disease?
Leiomyoma
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If you see bundles of smooth muscle hisologically are you likely looking at Leiomyoma or Leiomyosarcoma?
Leiomyoma
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What is Endometrial Hyperplasia?
Thickening of the endometrial lining due to excessive proliferation
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What is the term for the thickening of the endometrial lining due to excessive proliferation?
Endometrial hyperplasia
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How does Endometrial Hyperplasia manifest itself?
Abnormal uterine bleeding
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What is the cause of Endometrial hyperplasia?
Estrogen excess
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Wht other issues might a patien with Endometrial hyperplasia have and why?
- Due to excess Estrogen:
- obeisity
- anovulation
- polycystic ovaries
- exogenous estrogen
- estrogen secreting tumors of the ovaries
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What issues can increased Estrogen cause?
Obesity, Anovulation, polycystic ovaries, exogenous estrogen, etrogen secreting tumors of the ovaries
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Endometrial hyperplasia can be what three types histologically?
Simple, Complex or Atypical
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Grading of Endometrial hyperplasia as Simple or complex is based on what?
The complexity of the glands
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Grading of Endometrial hyperplasia as atypical is based on what?
The atypical appearance of the cells lining the gland
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What risk does Atypical endometrial hyperplasia incur?
20-25% risk of developing cancer
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Histologically what would you expect to see froma patient with Endometrial hyperplasia?
Galnds more closely packed together than normal
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What Cancer makes up 7% of all invasive cancers in women?
Endometrial cancer
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Endometrial cancer makes up what percent of all invasive fcancers on females?
7%
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