PTG 105- Exam 3- lecture 18-2

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  1. What is the term for abnormal bleeding in the uterus without a lesion?
    Dysfunctional uterine bleeding
  2. What is the definition of Dysfunctional uterine bleedsing?
    Ueterine bleeding sans lesion
  3. Edometrial biopsy can be used to test for Dysfunctional uterine bleeding (T/F)?
    False, it does not show the disease
  4. Why does Dysfunctional uterine bleeding occur?
    Hormonal changes
  5. Hormonal changes can cause what uterine disease?
    Dysfunctional uterine bleeding
  6. What test is not useful in testing for dysfunctional uterine bleeding?
    Endometrial biopsy
  7. Edometrial polyps are usually cancerous (T/F)?
    False, they are usually benign
  8. What re the symptoms of Endometrial polps?
    • Intermestrual bleeding
    • Menorhagia
    • Postmenstrual bleeding
  9. What dises is indicated by postmenstrual bleeding, Menorrhagia and Intermenstrual bleeding?
    Endometrial polyps
  10. Tamoxifen is used for what?
    Treatment of breast cancer
  11. What are endometrial polyps associated with?
    • Tamoxifen
    • Heperestrinism
  12. Tamoxifen and Heperestrinism are associated with what disease?
    Endometrial polyps
  13. Describe endometrial glands in a pateint that has endometrial polyps:
    Normal architecture or cystically dialated
  14. What is Leiomyoma?
    Common benign tumor of the female reproductive tract smooth muscle
  15. How common are Lieomyomas?
    30-50% of women will develop in their reproductive life
  16. 30-50% of women will develop what disease during their reproductive life?
  17. What is the etiology of  Leiomyoma?
    Genetics, Estrogen and OCP
  18. What are the symptoms of Leiomyoma?
    • Asymptomatic
    • Miscarraige
    • Pressure symptoms
    • Menorrhagia
    • pain
  19. What female urogenital disease has teh following manifestations:
    Asymptomatic, pain, menorrhagia, pressure symptoms, miscarriage?
  20. What is the term for a malignant tumor of the uterine smooth muscle?
  21. What is Leiomyosarcoma?
    Malignant tumor of the uterine smooth muscle
  22. What are the manifestations of Leiomyosarcoma?
    Cellular atypia, nuclear pleomorphism, increased mitotic activity and necrosis
  23. What disease is indicated by the following manifestations: Nuclear pleomorphism, necrosis, increased mitotic rate and cellular atypia?
  24. What does a Leiomyoma look like grossly?
    Well defined rubbery mass with "whorled out" cut surface
  25. A well defined rubbery mass with a "whorled out" cut surface is likely what disease?
  26. If you see bundles of smooth muscle hisologically are you likely looking at Leiomyoma or Leiomyosarcoma?
  27. What is Endometrial Hyperplasia?
    Thickening of the endometrial lining due to excessive proliferation
  28. What is the term for the thickening of the endometrial lining due to excessive proliferation?
    Endometrial hyperplasia
  29. How does Endometrial Hyperplasia manifest itself?
    Abnormal uterine bleeding
  30. What is the cause of Endometrial hyperplasia?
    Estrogen excess
  31. Wht other issues might a patien with Endometrial hyperplasia have and why?
    • Due to excess Estrogen:
    • obeisity
    • anovulation
    • polycystic ovaries
    • exogenous estrogen
    • estrogen secreting tumors of the ovaries
  32. What issues can increased Estrogen cause?
    Obesity, Anovulation, polycystic ovaries, exogenous estrogen, etrogen secreting tumors of the ovaries
  33. Endometrial hyperplasia can be what three types histologically?
    Simple, Complex or Atypical
  34. Grading of Endometrial hyperplasia as Simple or complex is based on what?
    The complexity of the glands
  35. Grading of Endometrial hyperplasia as atypical is based on what?
    The atypical appearance of the cells lining the gland
  36. What risk does Atypical endometrial hyperplasia incur?
    20-25% risk of developing cancer
  37. Histologically what would you expect to see froma patient with Endometrial hyperplasia?
    Galnds more closely packed together than normal
  38. What Cancer makes up 7% of all invasive cancers in women?
    Endometrial cancer
  39. Endometrial cancer makes up what percent of all invasive fcancers on females?
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PTG 105- Exam 3- lecture 18-2
2013-04-09 14:18:53
PTG 105 Exam lecture 18

PTG 105- Exam 3- lecture 18-2
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