PTG 105 -Exam 3- Lecture 16-5

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kyleannkelsey
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PTG 105 -Exam 3- Lecture 16-5
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2013-04-09 16:11:48
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PTG 105 Exam Lecture 16
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PTG 105 -Exam 3- Lecture 16-5
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  1. Carrier state of Hep B is indicated by what?
    Presence of HBs antigens for over 6 months
  2. Anti HBs confers what?
    lifelong immunity
  3. Lifelong immunity for HBs can be conferd by what?
    Anti-HBs
  4. What serum levels indicate active viral replication in Hep B?
    HBe antigen and HBV DNA
  5. HBe antigens and HBV DNA indicate what in a person with Hep B?
    Active disease state, repliating virus
  6. What percent of Hep B sufferers have complete recovery and subclinical disease?
    60%
  7. What percent of Hep B sufferers have acute hepatitis, but completely recover?
    25%
  8. What percent of Hep B cases end with the person as a healthy carrier?
    10%
  9. What percent of Hep B infected individuals have a persistent infection?
    5%
  10. Of those Hep B sufferers that have a persistant infection, what percent recover eventually?
    90%
  11. Of those Hep B sufferers with a persistant infection, what percent develop chronic hepatitis?
    10%
  12. Of the 10% of Hep B sufferers with a chronic infection, 10% develop hepatitis , what percent of those with hepatitis develop cirrhosis?
    20-50%
  13. Massive or fulmitant hepatic failure is a common outcome of Hep B?
    False, it is uncommon
  14. How is an acute infection of Hep B treated?
    no treatment availbale, just supportive
  15. What type of Hep B infection has no treatment available (only supportive)?
    Acute infection
  16. What treatments are availbale for chronic Hep B infection?
    inerferon alpha-2a and anti-virals
  17. What type of Hep B infection can be treated with antivirals and interferon alpha-2a?
    Chronic hep b infection
  18. Hep C is what type of virus?
    DNA virus
  19. What is the incubation period of Hep C?
    2 weeks to 6 months
  20. How does Hep C spread?
    Similar to Hep B (blood, fluids, etc.)
  21. What strain of Hep B causes the most cases of post-transfusion hepatitis?
    Hep C
  22. Hep B or Hep C is more likley to develop into chronicity, Cirhosis and carcinoma?
    Hep C
  23. The symptoms of Hep C are similar to what other Hepatitis strain?
    Hep B
  24. What two main viral strains of hepatitis are most likley to lead to hepatocellular carcinoma?
    B and C
  25. What is the chance of aquiring Hep C from a blood transfusion (currently with advanced screen methods)?
    1 in 2 million units
  26. Before 1992 what was the leading method for aquiring Hep C?
    blood transfusion
  27. How do you screen for Hep C?
    • look for anti-HCV by:
    • EIA or RIBA

    • Tests to detect presence of virus:
    • HCV RNA via PCR
  28. What is RIBA?
    recombinant immunoblot assay
  29. What Hepatits strain would you test for using EIA, RIBA or PCR?
    Hep C
  30. What is the treatment for chronic Hep C?
    pegylated interferon and ribavirin
  31. What Hep strain/type would you treat with pegylated interferon and ribavirin?
    Hep C
  32. What are the characteristics of Hep Delta virus?
    • Requires Hep B for replication
    • Infection only in those with HBV
  33. Which Hepatitis strain requires a current infection of Hep B?
    Hep Delta
  34. HEV is similar to what other hep strain?
    Hep A
  35. Describe the characteristics of Hep E?
    • acute
    • self-limiting
    • no chronicity or carrier state
    • can cause fulmitant hep in preganant women
  36. What Hep strain can cause fulmitant hep in pregnant women?
    Hep E

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