PTG 105- Exam 3- Lecture 19 - 3

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PTG 105- Exam 3- Lecture 19 - 3
2013-04-09 20:09:58
PTG 105 Exam Lecture 19

PTG 105- Exam 3- Lecture 19 - 3
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  1. Describe Porliferative fibrocystic change?
    • epithelial hyperplasia
    • sclerosisng adenosis
    • 1-5 times increased risk of breast cancer
  2. Which type of fibrocystic change increased the risk of breast cancer by 1-5 times?
  3. Which type of Fibrocystic change includes epithelial hyperplasia and sclerosing adenosis?
  4. Mammograms can pick up calcifications (T/F)?
  5. What is epithelial hyperplasia, as in fibrocystic change?
    proliferation of the duct epithelium
  6. What is sclerosing adenosis, as in fibrostic change?
    proliferation of the breast acini with stromal fibrosis
  7. What is the term for proliferation of breast acini with stromal fibrosis?
    Sclerosis adenosis
  8. What is the term for proliferation of the duct epithelium?
    Epithelial hyperplasia
  9. What group is fibroadenoma most common in?
    age = 20s and 30s
  10. What does a fibroadenoma feel like?
    Freely moveable well defined mass
  11. A fibroadenoma is biphasic (T/F)?
    True, it involves both the glands and stroma
  12. Because a fibroadenoma involves both the tissues of the stroma and glands it is reffered to as:
  13. How si fibroadenoma treated?
    local excision
  14. A shrply demarcated border of a neoplasm in the brast indicates what type of tumor?
  15. What disease looks like "Chinese letters" histologically?
  16. Describe a Papilloma:
    Proliferation of duct epithelium in the lumen
  17. What are symptoms of Papilloma?
    Nipple bleeding
  18. What percent of nipple bleeding is due to papilloma?
  19. Phyllodes tumor is what?
    A biphasic, usually benign tumor taht involves the proliferation of the glands and stroma
  20. Fibroadenoma or Phyllodes tumor are more common?
  21. What size are phyllodes tumors?
    3-4 cm, but can grow to massive size
  22. What age group is susceptible to Phyllodes tumor?
    50-60 years
  23. What does the tissue look like in a patien t with Phyllodes tumor?
    Leaf like architecture
  24. What type of tumor has a leaf like architecture?
  25. Phyllodes tumor is malignant (T/F)?
    False, it is usally benign and rarely malignant
  26. How is phyllodes tumor cured?
    Local excision
  27. How many women will develop breast cancer?
    1 in 9
  28. How many women will die of breast cancer?
    1 in 33
  29. What is the most common cancer in women in the US?
    Breast cancer
  30. What is the second leading cause of cancer deaths in the US?
    Breast cancer
  31. Howmany men compared to women get breast cancer?
  32. What percentage of women with breast cancer are over the age of 50 years?
  33. 75% of women with breast cancer have this in common:
    Are over the age of 50
  34. The incidence of breast cancer is increasing or decreasing around the world?
    Increasing worldwide
  35. What percent of breast cancers are due to genetics?
  36. 3-10% of all breast cancers are due to what?
  37. 2/3 of hereditary breast cancers are due to what two genes?
    BRCA 1 and 2
  38. What proportion of hereditary breast cancers are due to BRCA 1 and 2?
  39. Mortality of breast cancer increases with what other factor?
  40. Incidence increases with age until _____ when it begins to decline.
  41. What are thesix signs of breast cancer?
    • Lump
    • Enlarged local lymph nodes
    • exzema of the nipple
    • nipple discharge
    • nipple retration
    • orange peel look (advanced stage)
  42. What lymph nodes will likely be swollen in a breast cancer patient?
    Axillary nodes in the axillanad subclavicular area