PTG 105- Exam 3- Lecture 20 - 1
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Name the endocrine organs of the body:
- adernal glands
What are no most enodcrine disorders due to?
Hyper or Hypo function of a gland
Adenohypophysis is also called what?
Neurohypophysis is also called what?
The adenohypophysis produce what six hormones?
The neurohypophysis produces what hormones?
ADH and Oxytocin
Where are oxytocin and ADH produced?
What are diseases cause Hyperpituitarism?
- carcinoma of pituitary
Adenoma, carcinoma of pituitary and hyperplasia can all cause what?
What is the most common cause of Hyperpituitarism?
What are the causes of Hypopituitarism:
- Ischemic injury
Surgery, radiation or ischemic injury can all cause what?
Panhypopituitarism can be caused by what four things?
- Pituitary neoplasm
- Postpartum hypotension
- Surgical removal
- destructive processes (sugery, radiation)
Postpartum hypotension can cause what complication that leads to hypopituitarism?
SHeehan syndrome = infarction of the gland
What is infarction of the pituitary called?
How does Panhypopituitarism manifest itself?
- Adrenocortical insufficiency
- Decreased pigmentation
- Decresed lactation
- Decreased growth in children
- Decreased sexual function (libido)
What disease can cause dwarfism?
What is the treatment for panhypopituitarism?
What are the risks if Panhypopituitarism is left untreated?
Selective hypofunctioning of posterior pituitary can lead to what disease?
Diabetes insipidus is due to a deficiency in what hormone?
When ADh is low what disease may be caused?
What are two types of Hyperfunctioning pituitary disscussed in class?
- GH secreting Adenoma
Prolactinoma and GH secreting adenomas may cause what type of altered pituitary function?
What is Prolactinoma?
Prolactin producing adenoma
Who is at greatest risk for Prolactinoma?
Women of child bearing age
What are the symptoms of Prolactinoma?
- Galactorrhea (abnormal lactation)
- Low libido
Galactorrhea is what?
What is the term for abnormal lactation?
What is the cause for someone who has Galactorrhea, amenorrhea, anovulation, infertility and loss of libido?
What hormone is responsible for normal lactation?
What does Growth hormone secreting adenoma or the pituitary cause?
Gigantism or Acromegaly
Gigantism and Acromegaly are caused by what disease?
Growth hormone secreting adenoma of the pituitary
Gigantism is found in what group of patients?
Acromegaly is found in what group of patients?
What are the manifestations of acromegaly?
- Large hands
- coarse facial features
- diabetes mellitus
- muscle weakness
- Cardiac failure
Large hands, hypertension, cardiac failure, muscle weakness, diabetes mellitus and coarse facial features are all manifestations of what disease?
What lab test is there for Gigantism and Acromegaly?
GH increased in serum
What is the treatment for GH secreting adenoma/Gigantism/Acromegaly?
Pituitary gigantism includes what specific type of course facial features?
How is apituitary adenoma diagnosised?
What are the causes of reduced ADH production/Diabetes insipidus?
metastic neoplasm, inflammation or trauma to the posterior pituitary
How does Diabetes Insipidus manifest itself?
- Polydipsia (increased intake of fluids)
What is polydipsia?
Increased intake of fluids
What would you suspect a patient had if they were suffering from polyurea and polydispia?
What is the treatment for Diabetes insipidus caused by the posterior pituitary?
- Hormone replacement
What is a goiter?
Enlargment of the thyroid gland
The thyroid follicle contains what?
The hormone is contained where inside the thyroid?
The thyroid follicle
An enlarged thyroid is called what?
What does T4 do?
- increase cellular metabolism
- effect brain and other organs nutritionally
What does T3 do?
Same as T4, nutritional metabolic control
What does Calcitonin do?
- Increases deposition of Ca and phosphate into the bone
- Lowers blood Ca
What hormone lowers blood Ca and increases Ca and phosphate deposition in the bone?
What hormones are produced by the thyroid gland?
T4, T3 and Calcitonin
What are causes of Hypothyroidism?
- Hashimoto's disease
- Iodine deficiency
What are the manifestations of of Hypothyroidism?
- Decreased activity
- Intolerance to cold
- Dry skin/hair
- Decreased T3, T4
- Elevated TSH
- Decreased I131 uptake
What would you like to do?
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