Card Set Information
Ethers Aldehydes Ketones
Ethers, Aldehydes and Ketones (coming soon)
How do you make an Ether?
B. Williamson Ether Synthesis
What must the starting material be for Williamson Ether Synthesis?
A primary (best) or secondary alcohol
What kind of alkyl halide is required in a Williamson Ether Synthesis?
A 1° alkyl halide
What are the rules of Ether rxns?
A. If the starting ether has only 1° or 2° carbons the halide will do SN
to the less substituted carbon
B. If the starting ether has 3° carbon the halide will do SN
to the most substituted carbon
How does the Oxymercuration make the ether?
It adds the R-OH to the most substituted carbon and then the NaBH
takes the H off the alcohol to make the ether.
What does PBr
It kicks off an alcohol
What adds 2 OH groups to an alkene?
What does NaBH
It reacts with carbonyls except for Carboxylic acids and Esters, to make an alcohol
What does PCC do to a primary alcohol?
It turns it into an aldehyde
What does ozonolysis (O
, DMS) do?
Make 2 carbonyl groups on both sides of an alkene after breaking it.
How do you make a ketone from a 2° alcohol?
, heat and acetone (aq)
How do you turn a carbonyl into an alcohol?
, MeOH or H
What does Ph
It replaces the carbonyl with an alkene and the R group
What does CrO3 H2SO4 do to a 1° alcohol
Turns it into a carboxylic acid
What does POCl3 do?
Turns a 2° alcohol to an alkene to the least sub carbon
How do you turn a carbonyl into an acetal? How do you turn it back?
A. H+, 2ROH
B. H+, H2O
Mechanism for forming acetal
How do you get rid of a carbonyl?
1) H+, H2NNH2
2) KOH, H2O (100-200°C)
How do you turn an alkyne to an aldehyde?
How do you turn an alkyne into a ketone?
How do you turn an ester into a carboxylic acid?