Slate Training - Module 3

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Author:
bwallis
ID:
212796
Filename:
Slate Training - Module 3
Updated:
2013-04-19 11:05:29
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Testopel
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Mod 3
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  1. Prolactin Level Test (2)
    • Determines possible tumor in pituitary gland
    • High serum prolactin level may indicate pituitary dysfunction
  2. Hypogonadism - definition and facts (4)
    • condition in men where testes does not produce enough testosterone
    • 13 million US men have it
    • can be born with it or develop it through injury or infection
    • Low T before puberty can effect growth and development
  3. Secondary Hypogonadism
    result of pituitary or hypothalamus dysfunction
  4. Normal Hypothalamus function (3)
    • produces GnRH
    • signals pituitary gland to make FSH and LH
    • LH then signals testes to produce testosterone
  5. Klinefelters Syndrome (2)
    • 2 or more X chromosomes are present with one Y
    • The extra X causes abnormal development of testicles which causes underproduction of testosterone
  6. Causes of Secondary Hypogonadism (6)
    • Kallman Syndrome
    • Obesity
    • Opiate pain meds
    • HIV/Aids
    • Inflammatory Disease
    • Pituitary Disorder
  7. Testosterone Circulates in blood in 3 forms...
    • 68% bound tightly to SHBG
    • 30% weakly bound to albumin
    • 2% free testosterone
  8. Bioavailable Testosterone
    Testosterone available to act on the androgen receptor
  9. Equilibrium Dialysis (2)
    • Measurement of Free Testosterone
    • Done in specialty labs
  10. FSH Blood Test (3)
    • High FSH levels are due to primary testiculay failure
    • Low levels mean pituitary or hypothalmic disorder
    • can be due to injury or testicular growth defect
  11. Serum LH Blood Test (3)
    • levels are measured when serum prolactin levels are normal or low to differentiate testicular failure from pituitary or hypothalmic abnormality
    • LH is usually high in patients w/ primary testicular disorder
    • when serum Tesosterone levels are low and LH is high it is time for TRT
  12. Hemochromatosis
    Too much iron in blood
  13. Mumps Orchitis (3)
    • mumps infection involving testicles
    • occurs during adolesence or adulthood
    • long-term testicular damage may occur
  14. Kallman Syndrome (3)
    • Abnormal development of Hypothalamus
    • Associated with impaired development of smell (ansomia)
    • can cause hypogonadism and secondary hypogonadism
  15. Causes of Hypogonadism (7)
    • Klinefelters Syndrome
    • Undescended testicles
    • Mumps Orchitis
    • Hemochromatosis
    • Injury to testicles
    • Cancer treatment
    • Normal Aging
  16. ADAM (2)
    • Androgen Deficiency in Aging Male
    • Questionnaire to screen for Low T
  17. Diagnosing Hypogonadism (2)
    • ADAM (signs and symptoms)
    • Blood Tests
  18. Symptoms of Low T (5)
    • Lack of Energy
    • Depressed Mood
    • Low Libido
    • Loss of Muscle Mass
    • Loss of Bone Density
    • Anemia
  19. When can Hypogonadism occur? (3)
    • Fetus
    • Adolesence/Puberty
    • Adulthood
  20. In adult onset hypogonadism, doctors will generally separate the signs and symptoms into...(3)
    • Sexual
    • Psychological
    • Physical
  21. Normal T range



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    300 - 1200 ng/dl



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