Immune System 3.27.13

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Immune System 3.27.13
2013-04-11 10:05:57
Bio 256 Exam

Immune system exam 4
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  1. Antimicrobial proteins
    • Enhance innate defenses
    • Include: interferon and complement proteins
  2. Interferon (IFN)
    molecule leaves infected cell and blocks viral reproduction in neighboring cell
  3. Anitbodies or Immunoglobulins (Ab/ Ig)
    • Small Y- shaped proteins excreted by B cells
    • Neutralize
    • agglutination and precipitation
    • opsonization
  4. opsonization
    marks foreign body for destruction by macrophages

    antibodies do this
  5. Complement protein
    • used against cellular antigens
    • destroys foreing substances
  6. Fever
    • Abnormally high body temp
    • body's thermostat is reset upwards in response to pyrogens
  7. Why are high fevers dangerouos
    denature enzymes
  8. Moderate fever causes
    • liver and spleen to sequester iron and zinc
    • increased metabolic rate- speeds tissue repair
    • body temp higher than ideal for microbial growth
  9. Adaptive defenses
    • recognizes specific foreign substances
    • acts to immobilize, neutralize, or destroy
    • amplifies inflammatory response
  10. Humoral
    antibody-mediated immunity
  11. cellular
    cell-mediated immunity
  12. Antigens
    mostly large, complex molecules not normally found in body
  13. Epitope
    the part of an antigen that is recognized by the immune system
  14. MHC proteins
    read more about this
  15. B lymphocytes
    oversee humoral immunity- antibody production
  16. T lymphocytes
    non-antibody- producing cells- cell- mediated arm of immunity
  17. Antigen-presenting cells
    • display antigens on MHCs
    • could technically be any cell but usually means cells with MHC ll