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souimet05
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Antimicrobial proteins
- Enhance innate defenses
- Include: interferon and complement proteins
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Interferon (IFN)
molecule leaves infected cell and blocks viral reproduction in neighboring cell
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Anitbodies or Immunoglobulins (Ab/ Ig)
- Small Y- shaped proteins excreted by B cells
- Neutralize
- agglutination and precipitation
- opsonization
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opsonization
marks foreign body for destruction by macrophages
antibodies do this
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Complement protein
- used against cellular antigens
- destroys foreing substances
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Fever
- Abnormally high body temp
- body's thermostat is reset upwards in response to pyrogens
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Why are high fevers dangerouos
denature enzymes
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Moderate fever causes
- liver and spleen to sequester iron and zinc
- increased metabolic rate- speeds tissue repair
- body temp higher than ideal for microbial growth
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Adaptive defenses
- recognizes specific foreign substances
- acts to immobilize, neutralize, or destroy
- amplifies inflammatory response
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Humoral
antibody-mediated immunity
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cellular
cell-mediated immunity
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Antigens
mostly large, complex molecules not normally found in body
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Epitope
the part of an antigen that is recognized by the immune system
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MHC proteins
read more about this
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B lymphocytes
oversee humoral immunity- antibody production
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T lymphocytes
non-antibody- producing cells- cell- mediated arm of immunity
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Antigen-presenting cells
- display antigens on MHCs
- could technically be any cell but usually means cells with MHC ll
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