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Which form of Vitamin D is present in the skin?
7-dehydrocholesterol that is converted to cholecalciferol (vitamin D3) - by UV light.
Which form of vitamin D is found in dietary source?
Cholecalciferol (vit D3)
What is the role of liver and kidney in vitamin D metabolism?
There is two successive hydroxylation of cholecalciferol in liver and kidney. Vitamin D3 is converted into 25-hydroxycholecalciferol by 25-hydroxylase in the liver. 25-hydroxycholecalciferol is converted into 1,25- dihydroxycholecalciferol by 1α-hydroxylase in the kidney.
Which form of the calcium is active ?
What is the difference in function of PTH and vitamin?
- Parathormone decreases the level of phosphate (parathormone pees phosphate)
- Vitamin D increases the level of phosphate (these both hormones work together to increase the calcium level , so our only target is to increase calcium level , but, there should be no effect on phosphate level, so to make the normal level, one hormone should increase the phosphate and one hormone should decrease the phosphate level,
Where is the PTH receptor in the gut located?
PTH receptor is absent in the the gut, so it has to take the help of vitamin D for its action, So, it induces the 1α-hydroxylase for its action, This 1,25-DHCC increases the absorption of calcium form gut.
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