Propofol

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Author:
Ritameeker
ID:
213277
Filename:
Propofol
Updated:
2013-04-13 18:46:01
Tags:
Propofol Diprovan Sedative Hypnotic
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Description:
Propofol
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  1. Propofol

    Names / Class
    Diprovan

    • Sedative
    • Hypnotic
  2. Propofol

    Mechanism of Action
    • Appears to inhibit GABA activity in the brain.
    • Ultra-short-acting non-barbituate, non-benzodiazopine hypnotic.
  3. Propofol

    Onset of Action
    Peak Effects
    Duration
    Half-Life
    • 9 - 36 seconds
    • 3 - 5 minutes
    • 6 - 10 minutes
    • 5 - 12 hours
  4. Propofol

    Indications
    Induction and maintenance of sedation
  5. Propofol

    Contraindications
    • Known hypersensitivity to the drug or to egg or soybean products.
    • Increased cranial pressure
  6. Propofol

    Precautions
    • Potent sedative:
    • use only with adequate monitoring
    • have resuscitative equipment available
  7. Propofol

    Side Effects
    • Pain on induction
    • Hypotension
    • Apnea
    • HA
    • Nausea / Vomiting
  8. Propofol

    Adult Dose
    • 2 mg/kg IV for induction/intubation
    • followed by 25 - 75 mcg/kg/minute as needed

    Procedural sedation requires less: 0.5 - 1.0 mcg/kg/minute
  9. Propofol

    Pedi Dose
    1 mg/kg IV
  10. Propofol

    Max Dose
    Unknown
  11. Propofol

    Routes / How Supplied
    • IV
    • PO

    Unknown

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