Vet 120 E1
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What is the definition of “laboratory animal” as used in VET 120?
Any animal used in research.
How does the USDA definition differ from 120 def?
The USDA definition excludes rats, mice and birds.
What is “laboratory animal science”?
The study of the use of animals in research, including husbandry and basic care, veterinary medicine of laboratory animals, and experimental techniques.
What is “laboratory animal medicine”?
The medical care of laboratory animals.
Is medical research on animals part of laboratory animal medicine?
What is the #1 animal used in research?
What is the #2 animal used in research?
What do the letters AALAS stand for?
American Association for Laboratory Animal Science
What does AALAS do?
Support animal research and animal welfare and provide education and certification of laboratory animal technicians and technologists.
What do the letters PETA stand for?
People for the Ethical Treatment of Animals
What does PETA do?
Support animal rights and oppose the exploitation of animals in research, food production, zoos and circuses, and as pets.
What do the letters ALF stand for?
Animal Liberation Front
What does ALF do?
Support animal rights and oppose the use of animals . ALF can use violent means to liberate animals and destroy research.
What do the letters AVMA stand for?
American Veterinary Medical Association
What does the AVMA do?
Support the health and welfare of all animals and establish criteria for appropriate euthanasia
What do the letters APHIS stand for?
Animal and Plant Health Inspection Service
What does APHIS do?
Enforce the Animal Welfare Act
What do the letters USDA stand for?
United States Department of Agriculture
What does the USDA do?
The USDA is the department in which APHIS is located, so it enforces the Animal Welfare Act.
What “animal rights”?
The belief that all animals should have the same rights as human animals.
What is “animal welfare”?
The belief that animals should receive the best possible care and that it is our responsibility to ensure that pain and distress are minimized.
Who has overall responsibility for an experiment?
The principle investigator
Who has overall responsibility for animal well-being?
The Lab Animal Veterinarian
Who is responsible for animal welfare?
List the three levels of AALAS certification from most basic to most skilled
- Assistant Laboratory Animal Technician
- Laboratory Animal Technician
- Laboratory Animal Technologist
What is the name of the document that defined the alternatives concept in animal
The Principles of Humane Experimental Technique
What is “replacement” and 3 examples?
Using something in place of a “higher” animal, such as a phylogenetically lower animal, invertebrate, cells or tissues, or inanimate model
What is reduction and 3 examples?
Using fewer animals- pilot project, healthy animals, good husbandry, statistical analysis of number needed…
What is “refinement” and 3 examples?
Decreasing pain & distress- decrease invasiveness, medications, humane end points, aseptic technique…
Why must an experimental design be detailed, reproducible and complete?
For validation and to build on the research
Where does most drug research begin?
Computer or chemistry lab
What is an “animal model”?
An animal that is used in an experiment to replace another animal (usually a human).
What do the letters ACUP stand for?
Animal Care and Use Plan
What is an ACUP?
A detailed written description of procedures that will be performed on an animal. It must be approved by the Institutional Animal Care and Use Committee.
What is an “experimental variable”?
What is being studied…a factor that is changed in an experiment.
What is a “nonexperimental variable”?
A factor that is not being studied in an experiment. It often occurs accidentally and may invalidate the experiment.
What is “validation”?
A formal procedure proving that something is true, effective or representative.
What do positive test results on animals mean?
That the experiment was effective and safe in animals. It means that the drug may be tested on people and may be safe and effective.
What is the name and date enacted of the first US regulation covering lab animals?
The Laboratory Animal Welfare Act of 1966.
When was the Improved Standards for Laboratory Animal Welfare Act enacted?
The Improved Standards for Laboratory Animals Act is an amendment of what regulation?
Animal Welfare Act
List 3 requirements of the Improved Standards for Lab Animal Welfare Act.List
- Training for personnel
- Animal Care and Use Plans
- Exercise for dogs
- Enrichment for nonhuman primates….
What do the letters IACUC stand for?
Institutional Animal Care and Use Committee
What does the IACUC do?
Supervise and approve all procedures done with animals at a research facility.
How often must the IACUC meet?
At least once every six months.
An animal must be observed how frequently?
At least once per day; more often if needed
- Dorsal: Back
- Ventral: Belly
- Distal: Far away
- Proximal: Twords body
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