1. Which step is commonly targeted in anticancer therapy?
2. How is glycolytic rate used in diagnostics?
3. Do we include [H+] in Keq calculation? Why or why not? When Q is <1 what happens?
4. Which steps in glycolysis are energetically coupled?
1. Glucose --G6P - prevents going to PPP, etc.
2. High glycolytic rates are seen in PET scans
3. No, because we assume [H+] is constant (10
). When Q<1, dG is negative --> favors forward rxn.
4. Those that require ATP, and glyceraldehyde + NAD+ --> 1,3 BPG).