MIC 541-Exam 4- Antimicrobials VI-3

What does pharmacologically better mean?

What is the hal-life of Clarithromycin/Azithromycin?

What protein synthesis inhibitor has a half life of 68 hours?

What are advantages of Clarithromycin and Azithromycin over Erythromycin?

What protein synthesis inhibitor leaves an unpleasant taste in the mouth (metallic)?

Erythromycin has what adverse effect?

What is the spectra of activity for Azithromycin?

Does Clarithromycin have improved H. influenzae action?

What are the downsides of Azithromycina nd Clarithromycin?

What are the two mechanisms of Macrolide resistance?

Which type of Macrolide resistance is inducible?

Which type of Macrolide resistance is constitutive?

What macrolide resistance mechamisn provides only moderate resistance?

What macrolide resistance mechanism provides a high level of resistance?

What is the modfaction made to modify the target (to create macrolide resistance)?

What is the spectrum of Chloramphenicol?

What inhibitor of protein synthesis is lipid soluble?

Why can Chloramphenicol access the humors of the eye and CSF well?

What is a good protein synthesis inhibitor for meningitis for penicillin allergic patients?

Chormaphenicol antagonizes what what other general type of drugs?

What specific bacteria does chloramphenicol have action against?

What antibiotic can be used for very serious conditions of Salmonella typhi and Bacteriodes fregilis?

What are the adverse effects of Chloramphenicol?

What are the predictable factors taht predispose a patient to Chloramphenicol adverse reactions?

What time period do adverse reactions to chloramphenicol occur?

What protein synthesis inhibitor can cause Haematological abnormalities?

What drug can cause aplastic anemia, gray baby syndrome and Fatality ?

What is Gray baby syndrome?

What symdrome causes green stools and gray skin in infants?

What proportion f babies die once showing signs of Gray baby Syndrome?

What are the 2 types of Haematological toxities?

Chloramphenicol causes problems in most patients (T/F)?
True False

Licomycin was discovered where?

Clindamycin is related to lincomycin how?

Clindamycin can commonly cause what deadly problem?

What drug can cause pseudomembranous colitis by C. difficile?

Is Clindamycin and alternative for Erythromycin?

Clindamycin is used by what group instead of Erythromycin?

What conditions do you use Clindamycin?

What antibiotic would you use to treat community aquired MRSA, CHRONIC staphylococcal osteomyelitis and Bacteriodes fragilis?

What is Glycycline a derivative of?

What is Tigecycline a derivative for?

What bacteria are susceptible to Tigecycline?

What is the general spectrum of Tigecycline?

Tigecycline has good tissue infiltration (T/F)?
True False

What should you not use Tigecycline against?