MIC 541-Exam 4- Antimicrobials VI-5

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kyleannkelsey
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213577
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MIC 541-Exam 4- Antimicrobials VI-5
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2013-04-14 23:34:18
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MIC 541 Exam Antimicrobials VI
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MIC 541-Exam 4- Antimicrobials VI-5
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  1. Daptomycin is used for what bacteria?
    MRSA
  2. Daptomycin is active against what?
    the cytoplasmic membrane
  3. What type of antibiotic is Daptomycin?
    Lipopeptide
  4. A Lipopetide has what type antibiotic activity?
    Membrane active
  5. What antibiotic is membrane active?
    • Daptomycin
    • Polymixins
  6. What is the spectrum for Daptomycin?
    Same as Vancomycin
  7. what is Daptomycin inactive in?
    Pneumonia
  8. What is the activity of Polymixins?
    Cell membrane active
  9. What is the problem of Polymixins?
    Very toxic
  10. What are the toxic issues of Polymixins?
    • irreversible or nearly irreverable neurotoxic effects
    • nephrotoxicity
  11. What pathogens may necessitate polymixin use?
    • P. aeruginosa
    • Acinetobacter
    • multiple resistant Enterobacteriaceae
  12. Resisatnce is emerging (T/F)?
    • True
    • Enterobacteriaceae especially
  13. What common use item has polymixins in it?
    Neosporin
  14. Neosporin is safe in the blood stream (T/F)?
    False, it is very dangerous because of the polymixins
  15. Patients with tuberculosis need to have what combination treatment?
    Two (never one) Anti-mycobacterial drugs at once to prevent resistance from developing
  16. What drugs should never be used alone:
    • Rifampin
    • Isonazid
    • Ethambutol
    • Paraminosalycylic acid
  17. What drugs indicate a mycobacterial infection that necessitates the use of two Antimycobacterial agents?
    Rifampin, Isonazid, Ethambutol and Paraaminosalysylic acid

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