Pharm

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Author:
shirljoa
ID:
214727
Filename:
Pharm
Updated:
2013-04-20 23:37:54
Tags:
Inhalationals
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Description:
Inhalationals
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  1. Ficks law of diffusion
    • diffusion= (P1-P2)(Area)(solubility)
    •                ----------------------------
    •              (membrane thickness)(sq.root of MW)
  2. Graham's law of diffusion
    rate of diffusion = 1/sq root of density = 1/sq root of molar mass3.
  3. Henry's Law
    amt of gas that will dissolve in a liquid is proportional to the partial press of the gas in the gas phase

    - allows determination of amts of gases (O2 and CO2) that will dissolve in blood
  4. Amt of O2 tha dissolves in blood
    0.003 ml/100 ml blood/mmHg partial press

    -so, if PaO2 is 300 mmHg, then 300 mmHg x 0.003= 0.9 ml O2/100 ml blood
  5. laminar flow
    change in P/airway resistance

    • airway resistance = 8 x length x viscosity
    •                             ------------------------
    •                          pi x radius to the 4th power
  6. Reynolds number
    • Re =linear velocity x diameter x fluid density
    •        --------------------------------------------
    •                        viscosity

    • low reynolds # (<1000) = laminar flow
    • high reynolds # (>1500) = turbulent flow
  7. poiseuille's law
    -used for laminar flow

    F = (pi r4 change P)/(8 viscosity length)
  8. Bernoulli's Principle
    • - r/t laminar flow
    • - based on total conservation of energy

    E = PV + mgh + 1/2 mv2

    in a narrowing, assuming constant flow, resistance & press will decrease in the narrowing

    • R = change in P/ F
    • R = 8(viscosity)(lenght)/(pi r4)
  9. causes of turbulent flow
    • - rough tubing walls or kinks
    • - flow through orifice
    • - high velocity flow

    flow exiting the narrowing becomes turbulent

    turbulent flow is inversely related to density
  10. absolute humidity
    mass of water vapr in a given volume of air
  11. relative humidity %
    (actual vapor press/saturated vapor press) x 100 
  12. ohm's law
    energy = current (amperes) x resistance (ohms)

    E = IR
  13. % inspired air
    • % of inhaled air that is occupied by anesthetic has
    • -controlled by anesthetic machine
  14. alveolar partial press
    used as a determinant of brain partial press

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