medchem III test IV cancer drug class

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medchem III test IV cancer drug class
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2013-04-22 18:31:25
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medchem III test IV cancer drug class
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  1. alkylating
    nitrogen mustards 7
    • chlorambucil - leukeran
    • bendamustine - treanda
    • estermustine - emcyt
    • cyclophosphamide - cytoxan
    • ifosamide - ifex
    • mechlorethamine - mustargen
    • melphalan - alkeran
  2. alkylating
    nitrosureas 3
    • carmustine - bicnu
    • lomustine - ceenu
    • streptozocin - zanosar
  3. alkylating other 4
    • dacarbazine (DTIC) - dome
    • busulfan - myleran
    • altretamine - hexalen
    • thiotepa
  4. anti-metabolite
    folic acid antagonist 3
    • methotrexate - trexall
    • pemetrexed - alimta
    • pralatrexate - folotyn
  5. methotrexate overdose 2
    • levoleucovorin - fusilev
    • carboxypeptidase - voraxaze
  6. anti-metabolite
    pyrimidine analogs 7
    • floxuridine -
    • cytarabine - cytosar
    • liposomal - depocyt
    • gemcitabine - gemzar
    • capecitabine - xeloda
    • azacitidine - vadaza
  7. anti-metabolite
    analogues of 2' - deoxycytidine
    decitabine - dacogen
  8. anti-metabolite
    purine analogs 7
    • mercaptopurine - purinethol
    • thioguanine
    • clardribine - leustatin
    • fludarabine - fludara
    • pentostatine - nipent
    • clofarabine - collar
    • nelarabine - arranon
  9. mitotic inhibitors
    vinca alkaloids 
    • vinblastine
    • vincristine
  10. mitotic inhibitors
    taxoids 3
    • paclitaxel - taxol
    • docetaxel - taxotere
    • carbazitaxel - jevtana
  11. mitotic inhibitor
    fermentation product - analogue of Epothilone B
    ixabepilone - ixempra
  12. mitotic inhibitors
    non-taxoid
    eribulin - halaven
  13. anti-tumor
    anthracycline 5
    • doxorubicin
    • daunorubicin
    • idarubicin
    • epirubicin - ellence
    • valrubicin - valstar
  14. anti-tumor
    mycin's 3
    • bleomycin
    • mitomycin - mitosol
    • dactinomycin - cosmegen
  15. anti-tumor
    anthracenedione
    mitoxantrone
  16. antineoplastic
    platinum coordination complexes
    • cisplatin
    • carboplatin
    • oxaliplatin - eloxatin
  17. substituted methylhydrazine
    procarbazine - matulane
  18. imidazotetrazine
    temozolomide - temoday
  19. ribonucleotide reductase inhibitor
    hydroxyurea - hydrea
  20. topoisomerase II inhibitor 2
    • etoposide¬†-etopophos- G2 specific
    • tenlposide - vumon- S & G2 specific
  21. topoisomerase I inhibitor 2
    • irinotecan - camptosar
    • 20-S-camptothecin
  22. anti-androgens 2
    • bicalutamide - casodex
    • nilutamide - nilandron
  23. progestins 2
    • megesterol - megace
    • medroxyprogesterone - depo provera
  24. GnRH agonists 3
    • leuprolide - lupron
    • goserelin - zoladex
    • triptorelin - trelstar depot
  25. GnRH antagonist
    degarelix - firmagon
  26. anti-estrogens 3
    • tamoxifen - soltamox
    • toremifene - fareston
    • fulvestrant - faslodex
  27. aromatase inhibitors 3
    • anastrozole - arimidex
    • exemestane - aromasin
    • letrozole - femara
  28. radiopharmaceuticals 4
    • sodium iodide (131 & 123)
    • strontium 89 chloride - metastron
    • samarium lexidronam - quadramet
  29. cytoprotective drugs 3
    • amifostine - ethyol
    • dexrazoxane - zinecand (totect)
    • mesna - mesnex
  30. retinoids 2
    • tretinoin - absorica
    • bexarotene - targretin
  31. protein kinase inhibitor
    imatinib - gleevec
  32. mTOR kinase inhibitor 2
    • temsirolimus - torisel
    • everolimus - afinitor (zortress)
  33. PML-RARa inhibitor
    trisenox - arsenic trioxide
  34. proteasome inhibitor 2
    • bortezomib - velcade
    • kyprolis - carfilzomib
  35. hedge hog pathway inhibitor
    vismodegib - erivedge
  36. histone deacetylase inhibitor 2
    • vorinostat - zolina
    • romidepsin - istodax
  37. oxidative stress inducer
    elesclomol
  38. CYP 17 testosterone inhibitor
    abiraterone - zytiga
  39. keratinocyte growth factor
    keplvance - palifermin

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