Microbiology

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Author:
creece
ID:
215500
Filename:
Microbiology
Updated:
2013-04-24 08:06:57
Tags:
Immune System
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Description:
Exam 4
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  1. Erythrocyte
    Red Blood Cells
  2. Thrombrocyte
    Platelets
  3. Leukocyte
    White Blood Cell
  4. Neutrophil
    • Granulocyte
    • 70% of circulating WBC
    • First WBC to infection
    • High mortality rate
    • Function- phagocyte; eat one microbe and die
  5. Basophil
    • Granulocyte
    • 1% circulating in blood stream
    • Release histamine and trigger inflammation
    • Allergies
  6. Mast Cells
    • Granulocyte
    • Fixed in tissues
    • Histamine granules
    • Prevalent in skin/respiratory tissues
    • Allergies
  7. Eosinophil
    • Granulocyte
    • Eukaryotic parasite response
    • Phagocytic
    • Release toxin granules
    • Increase allergy/asthma levels
    • Hygiene Hypothesis
  8. Monocyte
    • Agranulocyte
    • Found in blood tissue
    • Immature macrophages
    • Phagocyte
  9. Fixed Macrophage
    • Monocyte
    • Found in every tissue
    • (mostly spleen/lymph nodes)
    • Filters fluids through tissue
  10. Wandering Macrophages
    • Monocyte
    • Move with pseudopods
    • Go to infection to "clean up"
  11. T Cells
    • Lymphocyte
    • Cell mediated immunity (3rd line)
    •  
  12. B Cells
    • Lymphocyte
    • Make Antibodies
  13. Natural Kill Cells
    • Lymphocyte
    • Destroy target cells
  14. Chemokines
    • Cytokine
    • Chemotaxis signal for WBC
    • Induce migration of phagocytes into the infection site
  15. Interleukins
    • Cytokine
    • Tumor necrosis factor (TNF) acute proteins
    • Histamine- kinin, prostaglandins, leukotrienes-vasodilation
  16. Interferons
    • Cytokine
    • IFN anti-viral protein production
  17. Hematopoietic
    • Cytokine
    • Control blood stem cell differentiation to make new blood cells
  18. Antigen
    Large protein or polysaccharide
  19. Epitope
    Specific region on antigen that is bound by the antibody
  20. Hapten
    Small molecule that can trigger immune response if bound to large carrier molecule
  21. IgE
    • Bind to mast cells and basophils
    • Act as pseudo receptors
    • Involved in allergy response
  22. IgD
    • B cell surface receptors
    • Required to activate B cells
  23. IgA
    • Found in both secretions and on mucous membranes
    • Most abundant Ig in BODY
    • Neutralization which blocks attachment
    • Diamer
  24. IgM
    • Monomer form: B cell receptors
    • Pentameter form: secretions
  25. IgG
    • Major circulation Ab in serum (80%)
    • Secondary antibody for the SECOND exposure
    • Monomer: high affinity for binding; can enter tissues
    • Neutralized toxins and strongly triggers the complement cascade

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