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2013-04-24 11:53:13

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  1. basophil
    Gk, basis + philein, to love

  2. eosinophil
    Gk, eos, dawn, philein, to love

    allergy and parasitic
  3. neutrophil
    L, neuter + Gk, philein, to love

    formed by bone marrow and released into the circulating blood
  4. mast cell
    Mast, fattening; L, cella, storeroom

    related to the basophil
  5. dendritic cell
    branched like a tree, long filamentous

    antigen trapping
  6. Macrophage
    makros + phagein, to eat

    WBC which eats disease containing organisms
  7. Natural killer cells
    kill foreign substances and abnormal tissues
  8. Complement protein
    • A substance that is produced by a predecessor protein or in response to
    • the presence of foreign material in the body and that triggers or
    • participates in a complement reaction
  9. B cell
    comes from the bone marrow

    produces antibodies
  10. T cells
    come from the thymus gland

    produces cytokine, CTL
  11. antibody
    reacts with an antigen

    "anti-toxic body."
  12. CD4+ T cells
    helper cells
  13. B cell-->

    T cell-->

    • CDB+ T cell
    • CD4+ T cell
  14. antigen
    substance that causes production of an antibody
  15. Cytokine
    Greek ''cyto-'', cell; and ''-kinos'', movement

    • are any of a number of substances that are secreted by specific cells of
    • the immune system which carry signals locally between cells, and thus
    • have an effect on other cells
  16. Diapedesis
    to leap through
  17. phagosome
    eat + body/ vesicle

    a vacuole that contains the ingested matter of a phagocytic cell
  18. NK cells attack(cytotoxic granule release) when?
    1. Missing self

    2. induced self
  19. What is Missing vs. Induced self?
    Missing: no MHC-1 inhibition

    Induced: high expression of ligands for activation receptor allow activation to occur
  20. opsonization
    to make (cells) more susceptible to the action of phagocytes

    promote phagocytosis
  21. cytolysis
    dissolution of cells, esp by the destruction of their membranes

    make holes in the cell
  22. chemotaxis
    - movement by a cell or organism in reaction to a chemical stimulus

    taxis - a locomotor response toward or away from an external stimulus by a motile (and usually simple) organism
  23. 1. dilation of arterioles, release histamine, chemotaxis
    C3a, C4a, and C5a
  24. 2. opsonization of microbes
  25. 3. From MAC, cytolysis
    C5b, C6, C7, C8, C9
  26. What is composed of more than 12 types of plasma proteins?
    Complement system
  27. chemotaxis, cytolysis and opsonization
    Complement system
  28. What are the two types of Adaptive Immunity?
    cellular and humoral
  29. What is cellular immunity?
    T- cells: thymus

    thyme: a foreign(tissue) plant with infectious fungi, parasites

    virally infected cells, fungi, parasites and foreign tissues
  30. What is humoral immunity?
    humor= B humor is badly and extremely very infections

    B cells- bone marrow

    effective against bacterial infection and extracellular viral infection
  31. How long is time of infection for innate immunity? Adaptive immunity?
    innate: 12 hrs.

    adaptive: >5 days
  32. Generative lymphoid organs
    thymus, bone marrow, stem cell
  33. Peripheral lymphoid organs
    blood, lymph, mature T or B lymphocytes, lymph nodes, spleen mucosal and cutaneous lymphoid tissues
  34. epitope
    a site on an antigen at which an antibody can bind
  35. What in the antibody recognizes the epitope?
    antigen receptors