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Gk, basis + philein, to love
Gk, eos, dawn, philein, to love
allergy and parasitic
L, neuter + Gk, philein, to love
formed by bone marrow and released into the circulating blood
Mast, fattening; L, cella, storeroom
related to the basophil
branched like a tree, long filamentous
makros + phagein, to eat
WBC which eats disease containing organisms
Natural killer cells
kill foreign substances and abnormal tissues
- A substance that is produced by a predecessor protein or in response to
- the presence of foreign material in the body and that triggers or
- participates in a complement reaction
comes from the bone marrow
come from the thymus gland
produces cytokine, CTL
reacts with an antigen
CD4+ T cells
substance that causes production of an antibody
Greek ''cyto-'', cell; and ''-kinos'', movement
- are any of a number of substances that are secreted by specific cells of
- the immune system which carry signals locally between cells, and thus
- have an effect on other cells
to leap through
eat + body/ vesicle
a vacuole that contains the ingested matter of a phagocytic cell
NK cells attack(cytotoxic granule release) when?
1. Missing self
2. induced self
What is Missing vs. Induced self?
Missing: no MHC-1 inhibition
Induced: high expression of ligands for activation receptor allow activation to occur
to make (cells) more susceptible to the action of phagocytes
dissolution of cells, esp by the destruction of their membranes
make holes in the cell
- movement by a cell or organism in reaction to a chemical stimulus
taxis - a locomotor response toward or away from an external stimulus by a motile (and usually simple) organism
1. dilation of arterioles, release histamine, chemotaxis
C3a, C4a, and C5a
2. opsonization of microbes
3. From MAC, cytolysis
C5b, C6, C7, C8, C9
What is composed of more than 12 types of plasma proteins?
chemotaxis, cytolysis and opsonization
What are the two types of Adaptive Immunity?
cellular and humoral
What is cellular immunity?
T- cells: thymus
thyme: a foreign(tissue) plant with infectious fungi, parasites
virally infected cells, fungi, parasites and foreign tissues
What is humoral immunity?
humor= B humor is badly and extremely very infections
B cells- bone marrow
effective against bacterial infection and extracellular viral infection
How long is time of infection for innate immunity? Adaptive immunity?
innate: 12 hrs.
adaptive: >5 days
Generative lymphoid organs
thymus, bone marrow, stem cell
Peripheral lymphoid organs
blood, lymph, mature T or B lymphocytes, lymph nodes, spleen mucosal and cutaneous lymphoid tissues
a site on an antigen at which an antibody can bind
What in the antibody recognizes the epitope?