Benzodiazepine Drugs

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Author:
medic11student
ID:
21639
Filename:
Benzodiazepine Drugs
Updated:
2010-06-01 22:11:52
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Medic Drugs
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Description:
JHPC Medic 11
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  1. DIAZEPAM (VALIUM) / ANTI-ANXIETY, HYPNOTIC, ANTI-CONVULSANT, SEDATIVE
    • Diazepam is a benzodiazepine sedative and skeletal muscle relaxant
    • - reduces tremors
    • - induces amnesia
    • - reduces the incidence and recurrence of seizures
    • - relaxes muscle spasms in injuries
    • - produces amnesia for painful procedures (cardioversion)
  2. DIAZEPAM (VALIUM) / ANTI-ANXIETY, HYPNOTIC, ANTI-CONVULSANT, SEDATIVE Indications
    • - Major Motor Seizures
    • - Status epilepticus
    • - Premedication before cardioversion
    • - Muscle tremors due to injury
    • - Acute Anxiety
  3. DIAZEPAM (VALIUM) / ANTI-ANXIETY, HYPNOTIC, ANTI-CONVULSANT, SEDATIVE Contraindications
    • 1. shock
    • 2. coma
    • 3. acute alcoholism
    • 4. depressed vital signs
    • 5. obstretic patients
    • 6. neonates
  4. DIAZEPAM (VALIUM) / ANTI-ANXIETY, HYPNOTIC, ANTI-CONVULSANT, SEDATIVE Precautions
    • 1. psychoses
    • 2. depression
    • 3. myasthenia gravis
    • 4. COPD
  5. DIAZEPAM (VALIUM) / ANTI-ANXIETY, HYPNOTIC, ANTI-CONVULSANT, SEDATIVE Dosage/Route
    • Seizures: 5-10mg IV/IM
    • Acute Anxiety: 2-5mg IV/IM
    • Premedication: 5-15mg IV
  6. FLUMAZENIAL (ROMAZICON)/ BENZODIAZEPINE ANTAGONIST
    Flumazenial is a benzodiazepine antagonist used to reverse the sedative, recall, and psychomotor effects of diazepam, midazolam, and other benzos
  7. FLUMAZENIAL (ROMAZICON)/ BENZODIAZEPINE ANTAGONIST Indications
    Respiratory depression secondary to benzodiazepams
  8. FLUMAZENIAL (ROMAZICON)/ BENZODIAZEPINE ANTAGONIST Contraindications
    • 1. Hypersensitivity to flumazenial or other benzos
    • 2. Pts who take flumazenial for status epilepticus or seizures
    • 3. Seizure-prone patients during labor & delivery
    • 4. Tryicylic anti-depressant overdose
  9. FLUMAZENIAL (ROMAZICON)/ BENZODIAZEPINE ANTAGONIST Precautions
    • 1. Hepatic impairment
    • 2. Head Injury
    • 3. Alcohol & drug dependency
    • 4. Physical dependence on benzodiazepines
    • 5. Elderly
    • 6. Pregnancy & nursing mothers
  10. FLUMAZENIAL (ROMAZICON)/ BENZODIAZEPINE ANTAGONIST Dosage/Route
    0.2mg IV over 30sec/min, up to 1mg
  11. MIDAZOLAM (VERSED) / SEDATIVE
    • Midazolam is a short-acting benzodiazepine with:
    • 1. CNS depressant
    • 2. muscle relaxant
    • 3. Anti-convulsant
    • 4. Anterograde amnestic effects
  12. MIDAZOLAM (VERSED) / SEDATIVE Indications
    To induce sedation before cardioversion or intubation
  13. MIDAZOLAM (VERSED) / SEDATIVE Contraindications
    • 1. Hypersensitivity to benzos
    • 2. Narrow angle glaucoma
    • 3. Shock
    • 4. Coma
    • 5. Acute alcohol intoxication
  14. MIDAZOLAM (VERSED) / SEDATIVE Precautions
    • 1. COPD
    • 2. Renal impairment
    • 3. CHF
    • 4. elderly
  15. MIDAZOLAM (VERSED) / SEDATIVE Dosage/Route
    1 - 2.5 mg slow IV; 0.07 - 0.08mg/kg IM

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