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2013-05-01 07:53:48

Pharmacy Board Examination Reviewer
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  1. These are heterogenous group of compunds that are related more by their physical than their chemical properties
  2. Ester of fatty acid with alcohol
    simple lipid
  3. Ester of fatty acid with glycerol
  4. Ester of fatty acid with HMW alcohol
  5. Number of bond in saturated fatty acid
  6. Number of bond is unsaturated fatty acid
    Two or more
  7. 2 major role of fatty acid in body
    • as component of more complex membrane lipid
    • as major component of stored fat in form of triacylgycerol
  8. The tail of fatty acid contains carboxyl goup making this a hydrophobic. TRUE or FALSE
    • False
    • (Hydrocarbon Chain)
  9. The head of fatty acid contains hydrocarbon chain making it lipophilic. TRUE or FALSE
    • False
    • (Carboxyl group)
  10. -anoic means the fatty acid is
  11. -enoic means the fatty acid is
  12. Division of unsaturated fatty acid
    • Monounsaturated
    • Polyunsaturated
    • Eicosanoids
  13. Unsaturated fatty acid containing one double bond
    Monounsaturated fatty acid
  14. Unsaturated fatty acid containing two or more double bond
    Polyunsaturated fatty acid
  15. Derived from 20 carbon of polyenoic fatty acid comprising the prostanoids, leukotrienes and lipoxins
  16. It acts as local hormone and synthesized from eicosanoic polyunsaturated fatty acid to form cyclopentane ring
  17. A cyclopentane ring interrupted with an oxygen atom
  18. It signifies "9 position keto" in prostaglandin
    • E
    • ex: PGE2
  19. it signifies "9 position hydroxyl"
    • F
    • ex. PGF2a
  20. An eicosanoid which is formed from lipooxygenase pathway
    • Leukotriene
    • Lipoxin
  21. Leukotrienes composed of how many conjugated double bond?
    three conjugated bond
  22. Lipoxin composed of how many conjugated double bond?
    Four conjugated double bond
  23. Eicosanoid that causes bronchoconstriction and proinflammatory agent
  24. The main storage form of fatty acid
    • Triglycerides
    • Triacylglycerol
  25. Esters of trihydric alcohol glycerol and fatty acid
    • Triglyceride
    • Triacylglycerol
  26. Main lipid constituent of membrane
  27. Derivatives of phosphatidic acid
  28. It is important as intermediate in the synthesis of triacylglycerol
    Phosphatidic acid
  29. Other name of phosphatidylcholines
  30. Major constituent of the surfactant preventing adherence, due to surface tension, of the inner surface of the lungs
    Dipalmitoyl lecithin
  31. Other name of phosphatidylethanolamine
  32. Important constituent f the cell membrane phospholipids which serves as precursor of second messenger
    • Phosphatidylinositol
    • especially Phosphatidylinositol 4,5 biphosphate
  33. 2 second messenger produced by Phosphatidylinositol 4,5 biphosphate
    • Diacylglycerol
    • Inositol triphosphate
  34. Major lipid of mitochondrial membrane
  35. These are the intermediates in the metabolism of phosphoglycerol
  36. These are important in the metabolism and interconversions of phospholipids
  37. Found in oxidized lipoprotein and can promote atherosclerosis
  38. This is the 10% of the phospholipid of the brain
  39. Example of ethanolamines
    • Choline
    • Serine
    • Inositol
  40. It is the most potent alkyl ether plasmalogen
    Platelet Activating Factor
  41. It is synthesized in response to the formation of antigen IgE complexes on surface of white blood cells
    Platelet Activating Factor
  42. Lipid that found in the nervous system (brain and nerve tissue)
  43. Sphingosine + fatty acid
  44. This is the major sphingolipid in the brain and other nerve tissues (C24 fatty acid)
  45. Other name of galactosylceramide
  46. These are complex glycosphingolipids derived from glucosylceramide that contain in addtion of one or more of sialic acid
  47. Principal sialic acid found in human tissue
    Neuraminic acid
  48. The receptor in human intestine for cholera toxin
  49. Steroid contains what nucleus?
  50. The best steroid atherosclerosis and heart disease
  51. Major constituent of the plasma membrane and plasma of lipoprotein
  52. Precursor of vitamin D
  53. Lipid that participate in respiratory chain in mitochondrion
  54. It takes part in glycoprotein synthesis by transferring carbohydrates residueto aspargine residue of polypeptide
  55. It is the source of free radicals
    Lipid peroxidation
  56. Meaning of BHA
    Butylated hydroxyanisole
  57. Meaning of BHT
    Butylated hydroxytoluene
  58. Classification of Antioxidant
    • Preventive antioxidant
    • Chain breaking antioxidant
  59. Example of Preventive antioxidant
    • Catalase
    • Peroxidase
    • Selenium
    • Chelators of metal ion
  60. Peroxidase acts with what functional group?
  61. Selenium regulates what enzyme?
    Glutathione peroxidase
  62. Example of chain breaking antioxidant?
    • Superoxide dismutase
    • Vitamin E
  63. It is defined as the number of milligrams of KOH required to neutralize the fatty acid in one gram of fat
    Saponification number
  64. It is defined as the number of milligrams of KOH required to neutralize the free acid in one gram of fat
    Acid number
  65. Rancid fat has high acid number. TRUE or FALSE?
  66. It is defined as the number of milligram of KOH necessary to react with fatty acids which are in combination with glycerol in one gram of fat
    Ester number
  67. Acid value - Saponification value
    Ester value
  68. It is defined as the number of grams of iodine absorbed by 100grams of fat or oil
    iodine number
  69. it is a measure of degree of unsaturated of the fat or oil
    Iodine number
  70. It refers to the part of fat or oil that is insoluble in water or incapable of forming a soluble salt with alkali
    Unsaponification number
  71. It is defined as the number of milliliters of 0.1N alkali required to neutralize the volatile soluble fatty acid distilled from 5 grams of saponified and acidified fat
    Reichert - Meisel Number
  72. Chemical constant used todetermine adulteration of butterfat
    Reichert - Meisel Number
  73. It is defined as the number of milliliters of 0.1N alkali required to neutralize the volatile insoluble fatty acids distilled from 5 gram of saponified and acidified fat
    Polenske Number
  74. A measure of free hydroxyl group in fats or oils determined by the amount of potassium hydroxide used to neutralize the acetic acid formed by saponification of acetylated fat or oil
    Acetyl number