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Name some microcytic, hypochromic anemias
Fe deficiency, thalassemia, anemia of chronic disease (inflammation) of long duration
Labs in anemia of chronic disease.
Hgb most often 8-10. MCV and MCHC normal, so normocytic and normochromic but may progress to microcytic with time. Retic count often below normal. Not producing many new RBCs.
What MCV levels are considered microcytic?
below 80 fL
What MCV levels are considered macrocytic?
what does fL stand for in the MCV measurement?
How is MCV arrived at?
hematocrit divided by total RBCs multiplied by 10
Some causes of macrocytic anemia.
B12 or folate deficiency, alcoholism, liver dz
presence of abnormal cells in the circulation (eg, nucleated RBCs, blasts, atypical mononuclear cells) and/or abnormal increases or decreases in absolute counts for granulocytes, lymphocytes, monocytes, or platelets indicates what?
complex hematological dz such as leukemia, aplastic anemia, etc
Some lab findings in patient with sickle cell dz
- reticulocytosis of 3 to 15 percent, unconjugated hyperbilirubinemia,
- elevated serum lactate dehydrogenase, and low serum haptoglobin
What major lab finding is usually present with a hemolytic anemia.
Increase in reticulocyte count.
nml eosinophil percentage in CBC
normal neutrophil percentage in CBC
normal lymphocyte percentage in CBC
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